×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Adenocarcinoma
0.600
AlteredExpression
LHGDN
Regardless of serration, COX-2 overexpression was frequent (approximately 85%) in colorectal adenocarcinomas .
18230181 2008
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Adenocarcinoma
0.600
GeneticVariation
LHGDN
Polymorphism of -765G > C COX-2 is a risk factor for gastric adenocarcinoma and peptic ulcer disease in addition to H pylori infection: a study from northern India.
18330937 2008
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Adenocarcinoma
0.600
GeneticVariation
LHGDN
Cyclooxygenase-2 and inducible nitric oxide synthase gene polymorphisms and risk of reflux esophagitis, Barrett's esophagus, and esophageal adenocarcinoma.
18349295 2008
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Adenocarcinoma
0.600
AlteredExpression
LHGDN
We evaluated the prognostic significance of COX-2 expression in pancreatic adenocarcinomas .
18000398 2007
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Adenocarcinoma
0.600
Biomarker
LHGDN
COX-2 CA-haplotype is a risk factor for the development of esophageal adenocarcinoma.
17581270 2007
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Adenocarcinoma
0.600
Biomarker
LHGDN
Stromal myofibroblasts surrounding colon adenocarcinomas are an important source of VEGF and COX-2 production, while AP-1 and NF-kappaB transcription factors are activated and EGF-R is expressed in these cells and associated with COX-2 and VEGF production.
18032824 2007
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Adenocarcinoma
0.600
Biomarker
LHGDN
Cyclooxygenase-2 and epithelial growth factor receptor up-regulation during progression of Barrett's esophagus to adenocarcinoma .16521222 2006
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Adenocarcinoma
0.600
Biomarker
LHGDN
The association between lymph node metastasis and elevation of COX-2 was stronger in cases of AC than in cases of ASC (28.4 vs. 4.3%, P=0.023).
16111807 2006
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Adenocarcinoma
0.600
GeneticVariation
LHGDN
Relationship between cyclooxygenase 8473T>C polymorphism and the risk of lung cancer: a case-control study.
16542464 2006
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Adenocarcinoma
0.600
AlteredExpression
LHGDN
NF-kB pathway is activated and COX-2 expression is upregulated in stromal myofibroblasts surrounding colon adenocarcinomas compared to normal colon.
16215757 2006
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Adenocarcinoma
0.600
AlteredExpression
LHGDN
Thirty-seven out of 55 (67.3%) cervical adenocarcinomas significantly expressed COX-2 .
16681759 2006
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Adenocarcinoma
0.600
AlteredExpression
LHGDN
Expression of cyclooxygenase-2 in colorectal adenocarcinoma is associated with p53 accumulation and hdm2 overexpression.
15921850 2006
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Adenocarcinoma
0.600
GeneticVariation
LHGDN
-765G > C COX-2 polymorphism may be a susceptibility marker for gastric adenocarcinoma in patients with atrophy or intestinal metaplasia.
17006983 2006
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Adenocarcinoma
0.600
AlteredExpression
LHGDN
Seminal plasma promotes the expression of tumorigenic and angiogenic genes in cervical adenocarcinoma cells via the E-series prostanoid 4 receptor.
16574793 2006
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Adenocarcinoma
0.600
AlteredExpression
LHGDN
Molecular determinants in targeted therapy for esophageal adenocarcinoma.
16702519 2006
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Adenocarcinoma
0.600
AlteredExpression
LHGDN
Cyclooxygenase-2 induces EP1- and HER-2/Neu-dependent vascular endothelial growth factor-C up-regulation: a novel mechanism of lymphangiogenesis in lung adenocarcinoma.
14744769 2004
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Adenocarcinoma
0.600
AlteredExpression
LHGDN
Expression of cyclooxygenase-2 and clinicopathologic features in human gastric adenocarcinoma.
12532441 2003
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Adenocarcinoma
0.600
Biomarker
LHGDN
This study demonstrates a novel relationship between COX-2 expression and the neovasculature of human breast adenocarcinomas .
12855643 2003
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Adenocarcinoma
0.600
AlteredExpression
LHGDN
This suggests that Cox-2 -derived prostanoids promote aggressive behavior of adenocarcinomas of the stomach.
14616542 2003
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Adenocarcinoma
0.600
AlteredExpression
LHGDN
Correlation between expression of cyclooxygenase-2 and angiogenesis in human gastric adenocarcinoma.
12679908 2003
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Adenocarcinoma
0.600
AlteredExpression
LHGDN
Expression of cyclooxygenase-2 in cervical, endometrial, and ovarian malignancies.
12748469 2003
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Adenocarcinoma
0.600
AlteredExpression
LHGDN
In the same patient, COX-2 was negative in the hyperplasia region but positive in adenoma and adenocarcinoma regions, showing results reflecting the progression of the disease.
11920515 2002
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Adenocarcinoma
0.600
AlteredExpression
LHGDN
Frequent co-localization of Cox-2 and laminin-5 gamma2 chain at the invasive front of early-stage lung adenocarcinomas.
11891209 2002
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Adenocarcinoma
0.600
AlteredExpression
LHGDN
When tumor types were considered, there were more Cox 2 -positive adenocarcinomas compared with squamous cell carcinomas (21 of 51 adenocarcinomas [41%] vs. 9 of 46 squamous cell carcinomas [20%]; P = 0.03).
11920472 2002
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Adenocarcinoma
0.600
AlteredExpression
LHGDN
In general, the pattern of COX-2 expression increased from normal to PanIN to adenocarcinoma .
12162677 2002