Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6356
Gene Symbol: CCL11
CCL11
CUI: C0004096
Disease: Asthma
Asthma
0.700 GeneticVariation LHGDN The detection of statistical interaction models is one evidence of gene-gene interactions among Eotaxin genes, and this interaction is thought to influence the development of asthma. 18712274

2008

Entrez Id: 6356
Gene Symbol: CCL11
CCL11
CUI: C0004096
Disease: Asthma
Asthma
0.700 GeneticVariation LHGDN But, we observed that the A-384G polymorphism of Eotaxin 1 gene and T51C polymorphism of CCR3 gene are not associated with asthma. 17845580

2007

Entrez Id: 6356
Gene Symbol: CCL11
CCL11
CUI: C0004096
Disease: Asthma
Asthma
0.700 AlteredExpression LHGDN Most interestingly, for the first time, a highly significant association of the newly studied (GAAGGA)(n) hexanucleotide repeat with asthma (p = 3x10(-6)), log(10)TsIgE (p = 0.006) and eotaxin levels (p = 0.004) was observed. 17220216

2007

Entrez Id: 6356
Gene Symbol: CCL11
CCL11
CUI: C0004096
Disease: Asthma
Asthma
0.700 GeneticVariation LHGDN CCL11 SNPs and haplotypes were not associated with asthma among white or Hispanic families. 16461130

2006

Entrez Id: 6356
Gene Symbol: CCL11
CCL11
CUI: C0004096
Disease: Asthma
Asthma
0.700 AlteredExpression LHGDN Our results suggest that the polymorphisms of the eotaxin gene family are associated with the susceptibility of asthma and Eotaxin-3 might play the critical role for the recruitment of eosinophils and the maintenance of IgE levels. 15207712

2004

Entrez Id: 6356
Gene Symbol: CCL11
CCL11
CUI: C0004096
Disease: Asthma
Asthma
0.700 Biomarker LHGDN IL-5 and eotaxin levels were significantly correlated with eosinophil percentages in mild persistent asthma. 12915771

2003