Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 335
Gene Symbol: APOA1
APOA1
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.100 Biomarker LHGDN Our results show that apoA-I cleavage by TTR may affect HDL biology and the development of atherosclerosis by reducing cholesterol efflux and increasing the apoA-I amyloidogenic potential. 17693625

2007
Entrez Id: 335
Gene Symbol: APOA1
APOA1
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.100 Biomarker LHGDN Liver-directed AAV2.8-mediated gene transfer of wtApoA-I and ApoA-IM each significantly reduced atherosclerosis progression to a similar extent. 17475009

2007
Entrez Id: 335
Gene Symbol: APOA1
APOA1
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.100 Biomarker LHGDN The establishment of telomerase-immortalized Tangier disease cell lines indicates the existence of an apolipoprotein A-I-inducible but ABCA1-independent cholesterol efflux pathway. 15001567

2004
Entrez Id: 335
Gene Symbol: APOA1
APOA1
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.100 AlteredExpression LHGDN Long-term stable expression of human apolipoprotein A-I mediated by helper-dependent adenovirus gene transfer inhibits atherosclerosis progression and remodels atherosclerotic plaques in a mouse model of familial hypercholesterolemia. 12742997

2003