Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8626
Gene Symbol: TP63
TP63
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.400 Biomarker LHGDN The transcription factor p63 is commonly over-expressed in squamous cell carcinomas of the head and neck (SCCHN). 18194839

2008

Entrez Id: 8626
Gene Symbol: TP63
TP63
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.400 AlteredExpression LHGDN The results indicate that the overexpression of p63 in oral precancerous lesions and SCC in betel-quid chewers in Sri Lanka may be a useful marker for oral precancerous lesions. 18085379

2007

Entrez Id: 8626
Gene Symbol: TP63
TP63
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.400 Biomarker LHGDN Diffuse p63 positivity in basaloid squamous cell carcinoma suggests dysregulation of p63-positive stem cells in poorly differentiated squamous carcinoma. 15529180

2005

Entrez Id: 8626
Gene Symbol: TP63
TP63
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.400 AlteredExpression LHGDN To gain further information on the role of p63 expression in human tumours, we used quantitative real-time RT-PCR to study individual p63 isoforms in squamous cell carcinomas of the head and neck (SCCHN). 15201986

2004

Entrez Id: 8626
Gene Symbol: TP63
TP63
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.400 AlteredExpression LHGDN A large proportion of squamous cell carcinomas expressed p63 (96.9%), most showing strong positive nuclear immunoreactivity. 15551738

2004

Entrez Id: 8626
Gene Symbol: TP63
TP63
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.400 AlteredExpression LHGDN P63 and EGFR as prognostic predictors in stage IIB radiation-treated cervical squamous cell carcinoma. 14599865

2003

Entrez Id: 8626
Gene Symbol: TP63
TP63
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.400 AlteredExpression LHGDN p63 in laryngeal squamous cell carcinoma: evidence for a role of TA-p63 down-regulation in tumorigenesis and lack of prognostic implications of p63 immunoreactivity. 12379767

2002

Entrez Id: 8626
Gene Symbol: TP63
TP63
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.400 AlteredExpression LHGDN Our study indicates that (1) p63 and p73 expression may represent an early event in HNSC tumorigenesis, (2) the lack of correlation between p73 or p63 and p53 expression suggests an independent and/or compensatory functional role, (3) p73 expression may play a part in HNSC progression, and (4) p73 and p63 may function as oncogenes in the development of these tumors. 11957139

2002