DisGeNET - a database of gene-disease associations

Source: LHGDN

Disease: Colonic Neoplasms ×

Gene: SRC ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	6714
Gene Symbol:	SRC

SRC

CUI:	C0009375
Disease:	Colonic Neoplasms

Colonic Neoplasms

0.350

AlteredExpression

LHGDN

Src activity alters alpha3 integrin expression in colon tumor cells.

18839319

2009

Entrez Id:	6714
Gene Symbol:	SRC

SRC

CUI:	C0009375
Disease:	Colonic Neoplasms

Colonic Neoplasms

0.350

Biomarker

LHGDN

Decreased CHK protein levels are associated with Src activation in colon cancer cells.

17934522

2008

Entrez Id:	6714
Gene Symbol:	SRC

SRC

CUI:	C0009375
Disease:	Colonic Neoplasms

Colonic Neoplasms

0.350

AlteredExpression

LHGDN

PTP1B contributes to the oncogenic properties of colon cancer cells through Src activation.

17974954

2007

Entrez Id:	6714
Gene Symbol:	SRC

SRC

CUI:	C0009375
Disease:	Colonic Neoplasms

Colonic Neoplasms

0.350

Biomarker

LHGDN

Simultaneous inhibition of focal adhesion kinase and SRC enhances detachment and apoptosis in colon cancer cell lines.

12939401

2003