Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1806
Gene Symbol: DPYD
DPYD
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.600 AlteredExpression LHGDN Suppression of DPYD expression in RKO cells via DNA methylation in the regulatory region of the DPYD promoter: a potentially important epigenetic mechanism regulating DPYD expression. 17612628

2007

Entrez Id: 1806
Gene Symbol: DPYD
DPYD
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.600 GeneticVariation LHGDN Polymorphisms in the thymidylate synthase and dihydropyrimidine dehydrogenase genes predict response and toxicity to capecitabine-raltitrexed in colorectal cancer. 17203168

2007

Entrez Id: 1806
Gene Symbol: DPYD
DPYD
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.600 Biomarker LHGDN The relationship between survival and the expression of dihydropyrimidine dehydrogenase in patients with colorectal cancer. 16786143

2006

Entrez Id: 1806
Gene Symbol: DPYD
DPYD
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.600 AlteredExpression LHGDN We present a novel, standardized approach for TP, DPD, and TS mRNA quantification in archival tissue specimens and applied this to a large series of primary colorectal tumors. 16132996

2006

Entrez Id: 1806
Gene Symbol: DPYD
DPYD
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.600 AlteredExpression LHGDN Comparative analysis of thymidine phosphorylase and dihydropyrimidine dehydrogenase expression in gastric and colorectal cancers. 15069545

2004

Entrez Id: 1806
Gene Symbol: DPYD
DPYD
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.600 Biomarker LHGDN Both gene expression for orotate phosphoribosyltransferase and its ratio to dihydropyrimidine dehydrogenase influence outcome following fluoropyrimidine-based chemotherapy for metastatic colorectal cancer. 14562021

2003

Entrez Id: 1806
Gene Symbol: DPYD
DPYD
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.600 Biomarker LHGDN Thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expression levels: predictors for survival in colorectal cancer patients receiving adjuvant 5-fluorouracil. 14519634

2003

Entrez Id: 1806
Gene Symbol: DPYD
DPYD
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.600 Biomarker LHGDN DPD and TS expressions were measured by reverse transcription-PCR in surgically resected materials of primary colorectal tumors from 37 patients who went on to receive oral treatment of uracil and tegafur and leucovorin for either synchronous or metachronous metastatic diseases. 12576451

2003