Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 GeneticVariation LHGDN Genetic alterations of APC, K-ras, p53, MSI, and MAGE in Korean colorectal cancer patients. 17704924

2008

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 GeneticVariation LHGDN Prevalence of mutations in APC, CTNNB1, and BRAF in Tunisian patients with sporadic colorectal cancer. 18992635

2008

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 GeneticVariation LHGDN Missense polymorphisms in the adenomatous polyposis coli gene and colorectal cancer risk. 18612690

2008

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 AlteredExpression LHGDN Somatic APC inactivation mechanisms in sporadic colorectal cancer cases in Hungary. 18369740

2008

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 Biomarker LHGDN Regulation of the adenomatous polyposis coli gene by the miR-135 family in colorectal cancer. 18632633

2008

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 PosttranslationalModification LHGDN Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma. 18451217

2008

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 GeneticVariation LHGDN How the I1307K adenomatous polyposis coli gene variant contributes in the assessment of risk of colorectal cancer, but not stomach cancer, in a Turkish population. 17854661

2007

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 GeneticVariation LHGDN May the APC gene somatic mutations in tumor tissues influence the clinical features of Chinese sporadic colorectal cancers? 17653897

2007

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 GeneticVariation LHGDN The differentially mutational spectra of the APC, K-ras, and p53 genes in sporadic colorectal cancers from Taiwanese patients. 18265644

2007

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 GeneticVariation LHGDN The D1822V APC polymorphism interacts with fat, calcium, and fiber intakes in modulating the risk of colorectal cancer in Portuguese persons. 17556698

2007

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 Biomarker LHGDN The AAPC case, with an early onset of colorectal cancer. 16710723

2007

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 Biomarker LHGDN Smad3 deficiency promotes tumorigenesis in the distal colon of ApcMin/+ mice. 16951153

2006

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 Biomarker LHGDN APC E1317Q is not associated with Colorectal Cancer in a population-based case-control study in Northern Israel. 17119068

2006

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 AlteredExpression LHGDN Mutations in APC, CTNNB1 and K-ras genes and expression of hMLH1 in sporadic colorectal carcinomas from the Netherlands Cohort Study. 16356174

2005

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 GeneticVariation LHGDN APC, K-ras, and p53 gene mutations in colorectal cancer patients: correlation to clinicopathologic features and postoperative surveillance. 15943410

2005

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 GeneticVariation LHGDN Somatic mutations of APC gene in carcinomas from hereditary non-polyposis colorectal cancer patients. 15040027

2004

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 PosttranslationalModification LHGDN APC promoter hypermethylation contributes to the loss of APC expression in colorectal cancers with allelic loss on 5q. 15326380

2004

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 Biomarker LHGDN Role of APC and DNA mismatch repair genes in the development of colorectal cancers. 14672538

2003

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 AlteredExpression LHGDN Expressions of two adenomatous polyposis coli and E-cadherin proteins on human colorectal cancers. 12647217

2003

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 Biomarker LHGDN Adenomatous polyposis coli truncation alters cytoskeletal structure and microtubule stability in early intestinal tumorigenesis. 12504226

2003

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 GeneticVariation LHGDN Genetic analysis of familial colorectal cancer in Israeli Arabs. 12655564

2003

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 GeneticVariation LHGDN The APC/beta-catenin pathway in ulcerative colitis-related colorectal carcinomas: a mutational analysis. 11920497

2002

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 Biomarker LHGDN Beta-catenin expression and allelic loss at APC in sporadic colorectal carcinogenesis. 11956815

2002

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 GeneticVariation LHGDN Mutations in APC, Kirsten-ras, and p53--alternative genetic pathways to colorectal cancer. 12093899

2002

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 GeneticVariation LHGDN Mutation analysis of the adenomatous polyposis coli (APC) gene in northwest Spanish patients with familial adenomatous polyposis (FAP) and sporadic colorectal cancer. 11668620

2001