×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Colorectal Neoplasms
0.400
Biomarker
LHGDN
Three new nonsense mutations of MLH1 and MSH2 genes in Korean families with hereditary nonpolyposis colorectal cancer.
19100506
2009
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Colorectal Neoplasms
0.400
GeneticVariation
LHGDN
Reduced mRNA expression in paraffin-embedded tissue identifies MLH1- and MSH2-deficient colorectal tumours and potential mutation carriers.
18581137
2008
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Colorectal Neoplasms
0.400
AlteredExpression
LHGDN
Sporadic colon cancer: mismatch repair immunohistochemistry and microsatellite instability in Omani subjects.
18299982
2008
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Colorectal Neoplasms
0.400
GeneticVariation
LHGDN
MSH2 missense mutations and HNPCC syndrome: pathogenicity assessment in a human expression system.
18781619
2008
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Colorectal Neoplasms
0.400
Biomarker
LHGDN
Oncoprotein Bcl-2 and microsatellite instability are associated with disease-free survival and treatment response in colorectal cancer.
18949393
2008
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Colorectal Neoplasms
0.400
GeneticVariation
LHGDN
Germline MLH1 and MSH2 mutational spectrum including frequent large genomic aberrations in Hungarian hereditary non-polyposis colorectal cancer families: implications for genetic testing.
17569143
2007
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Colorectal Neoplasms
0.400
AlteredExpression
LHGDN
Novel hMSH2, hMSH6 and hMLH1 gene mutations and microsatellite instability in sporadic colorectal cancer.
16902769
2007
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Colorectal Neoplasms
0.400
GeneticVariation
LHGDN
High proportion of large genomic rearrangements in hMSH2 in hereditary nonpolyposis colorectal cancer (HNPCC) families of the Basque Country.
17582678
2007
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Colorectal Neoplasms
0.400
GeneticVariation
LHGDN
A novel MSH2 mutation in a Chinese family with hereditary non-polyposis colorectal cancer.
17333219
2007
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Colorectal Neoplasms
0.400
Biomarker
LHGDN
Risk of colon cancer in hereditary non-polyposis colorectal cancer patients as predicted by fuzzy modeling: Influence of smoking.
16874859
2006
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Colorectal Neoplasms
0.400
Biomarker
LHGDN
Loss of protein expression of hMLH1 and hMSH2 with double primary carcinomas of the stomach and colorectum.
16786121
2006
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Colorectal Neoplasms
0.400
AlteredExpression
LHGDN
Immunohistochemistry detects mismatch repair gene defects in colorectal cancer.
16684085
2006
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Colorectal Neoplasms
0.400
GeneticVariation
LHGDN
Clinical and molecular characteristics of hereditary non-polyposis colorectal cancer families in Southeast Asia.
15996210
2005
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Colorectal Neoplasms
0.400
AlteredExpression
LHGDN
The role of MLH1, MSH2 and MSH6 in the development of multiple colorectal cancers.
16106253
2005
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Colorectal Neoplasms
0.400
AlteredExpression
LHGDN
Correlation between hMLH1/hMSH2 and p53 protein expression in sporadic colorectal cancer.
15816455
2005
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Colorectal Neoplasms
0.400
Biomarker
LHGDN
The 5' region of the MSH2 gene involved in hereditary non-polyposis colorectal cancer contains a high density of recombinogenic sequences.
16086322
2005
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Colorectal Neoplasms
0.400
GeneticVariation
LHGDN
Oncogenic pathway of sporadic colorectal cancer with novel germline missense mutations in the hMSH2 gene.
12792735
2004
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Colorectal Neoplasms
0.400
GeneticVariation
LHGDN
Microsatellite instability (MSI) occurs from the mutational inactivation of the DNA mismatch repair genes, i.e. hMSH2 and hMLH1 in HNPCC, as well as from epigenetic inactivation of hMLH1 in sporadic colorectal tumors .
12808326
2003
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Colorectal Neoplasms
0.400
Biomarker
LHGDN
A636P is associated with early-onset colon cancer in Ashkenazi Jews.
12595050
2003
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Colorectal Neoplasms
0.400
GeneticVariation
LHGDN
Mutational analysis of promoters of mismatch repair genes hMSH2 and hMLH1 in hereditary nonpolyposis colorectal cancer and early onset colorectal cancer patients: identification of three novel germ-line mutations in promoter of the hMSH2 gene.
11782355
2002