Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
CUI: C0017638
Disease: Glioma
Glioma
0.400 Biomarker LHGDN A novel p53 rescue compound induces p53-dependent growth arrest and sensitises glioma cells to Apo2L/TRAIL-induced apoptosis. 18202704

2008

Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
CUI: C0017638
Disease: Glioma
Glioma
0.400 Biomarker LHGDN Novel therapeutic approaches using TRAIL or agonistic TRAIL receptor antibodies in combination with proteasome inhibitors may represent a promising approach to reactivate apoptosis in therapy-resistant high-grade gliomas. 18341587

2008

Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
CUI: C0017638
Disease: Glioma
Glioma
0.400 Biomarker LHGDN Rottlerin sensitizes glioma cells to TRAIL-induced apoptosis by inhibition of Cdc2 and the subsequent downregulation of survivin and XIAP. 15531913

2005

Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
CUI: C0017638
Disease: Glioma
Glioma
0.400 Biomarker LHGDN Roles of tyrosine phosphorylation and cleavage of protein kinase Cdelta in its protective effect against tumor necrosis factor-related apoptosis inducing ligand-induced apoptosis. 15774464

2005

Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
CUI: C0017638
Disease: Glioma
Glioma
0.400 Biomarker LHGDN Real-time imaging of TRAIL-induced apoptosis of glioma tumors in vivo. 14534533

2003

Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
CUI: C0017638
Disease: Glioma
Glioma
0.400 AlteredExpression LHGDN Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo. 12118245

2002