Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0021368
Disease: Inflammation
Inflammation 		0.380 Biomarker LHGDN Mice deficient for TGF-beta1 show a dramatic phenotype with severe multiorgan inflammation and die shortly after birth. 16298544

2009
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0021368
Disease: Inflammation
Inflammation 		0.380 AlteredExpression LHGDN IL-10 and TGF-beta redundantly protect against severe liver injury and mortality during acute schistosomiasis. 18981143

2008
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0021368
Disease: Inflammation
Inflammation 		0.380 Biomarker LHGDN Chronic inflammation associated with hepatitis C virus infection perturbs hepatic transforming growth factor beta signaling, promoting cirrhosis and hepatocellular carcinoma. 17596875

2007
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0021368
Disease: Inflammation
Inflammation 		0.380 GeneticVariation LHGDN Is low-frequency distribution of TGF-beta genotype associated with increased risk for end-stage renal disease? 17417945

2007
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0021368
Disease: Inflammation
Inflammation 		0.380 Biomarker LHGDN Further studies showed that inhibition of renal inflammation in TGF-beta1 transgenic mice was also associated with a marked upregulation of renal Smad7 and IkappaBalpha and a suppression of NF-kappaB activation in the diseased kidney (all P < 0.01). 15788474

2005
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0021368
Disease: Inflammation
Inflammation 		0.380 AlteredExpression LHGDN TGF-beta 1 downregulates CFTR expression and function in nasal polyps of non-CF patients. 15361357

2005
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0021368
Disease: Inflammation
Inflammation 		0.380 Biomarker LHGDN These data provide further support for the concept that differentiated macrophages play a protective role in the pathophysiology of gout, and they identify macrophage TGFbeta1 as a mediator of paracrine suppression during the resolution phase of inflammation. 15248227

2004
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0021368
Disease: Inflammation
Inflammation 		0.380 Biomarker LHGDN TGF-beta: receptors, signaling pathways and autoimmunity. 11826761

2002