Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0023418
Disease: leukemia
leukemia 		0.100 AlteredExpression LHGDN Monocytic leukemia zinc finger (MOZ) interacts with p53 to induce p21 expression and cell-cycle arrest. 19001415

2009
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0023418
Disease: leukemia
leukemia 		0.100 AlteredExpression LHGDN We found that CD154-expressing cells induced expression of CD95 and the BH3-interacting-domain death agonist (Bid) in CLL, regardless of whether the leukemia cells had functional p53. 16741250

2006
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0023418
Disease: leukemia
leukemia 		0.100 Biomarker LHGDN Human T cell leukemia virus type 1: the role of Tax in leukemogenesis. 16088313

2005
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0023418
Disease: leukemia
leukemia 		0.100 AlteredExpression LHGDN These observations identify mitochondrial activity, described by MTMP and ROS levels, as a critical intracellular determinant of the p53 stress sensitivity and suggest potential implications of this linkage in the mechanisms of chemoresistance of acute leukemia cells. 15705792

2005
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0023418
Disease: leukemia
leukemia 		0.100 GeneticVariation LHGDN Coexpression of p53 protein and MDR functional phenotype in leukemias: the predominant association in chronic myeloid leukemia. 15351976

2004
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0023418
Disease: leukemia
leukemia 		0.100 GeneticVariation LHGDN Our findings indicate that genetic alterations, such as p53 mutations, in stromal cells can increase stromal-derived support of leukemia growth. 12901974

2003
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0023418
Disease: leukemia
leukemia 		0.100 AlteredExpression LHGDN MDM2 and p53 in childhood acute lymphoblastic leukemia: higher expression in childhood leukemias with poor prognosis compared to long-term survivors. 11764099

2001
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0023418
Disease: leukemia
leukemia 		0.100 AlteredExpression LHGDN Noteworthy was the inverse relation between the higher proportion of p53 positive cells and low Bcl-2 positivity in some cases of acute leukemia. 11949843

2001