Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.400 AlteredExpression LHGDN Solamargine enhances HER2 expression and increases the susceptibility of human lung cancer H661 and H69 cells to trastuzumab and epirubicin. 18078328

2008
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.400 GeneticVariation LHGDN PF00299804, an irreversible pan-ERBB inhibitor, is effective in lung cancer models with EGFR and ERBB2 mutations that are resistant to gefitinib. 18089823

2007
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.400 GeneticVariation LHGDN EGFR, ERBB2, and KRAS mutations in Korean non-small cell lung cancer patients. 17321325

2007
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.400 GeneticVariation LHGDN Patterns of EGFR, HER2, TP53, and KRAS mutations of p14arf expression in non-small cell lung cancers in relation to smoking history. 17575133

2007
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.400 Biomarker LHGDN The aim of the study was to investigate a relation between p53 and HER2/neu expression in resected lung tumors and the response of those tumors to neoadjuvant chemotherapy. 16847810

2006
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.400 AlteredExpression LHGDN Differential expression of STAT5 and Bcl-xL, and high expression of Neu and STAT3 in non-small-cell lung carcinoma. 16959370

2006
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.400 AlteredExpression LHGDN Synchronous overexpression of epidermal growth factor receptor and HER2-neu protein is a predictor of poor outcome in patients with stage I non-small cell lung cancer. 14734462

2004
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.400 Biomarker LHGDN Effects of gefitinib on serum epidermal growth factor receptor and HER2 in patients with advanced non-small cell lung cancer. 15447984

2004
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.400 Biomarker LHGDN [Study on the expression of C-erbB-2 gene in coal miners with pneumoconiosis complicated by pulmonary cancer]. 14761474

2003
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.400 Biomarker LHGDN Clinical value of p53, c-erbB-2, CEA and CA125 regarding relapse, metastasis and death in resectable non-small cell lung cancer. 14566828

2003
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.400 AlteredExpression LHGDN Lung tumorigenesis associated with erb-B-2 and erb-B-3 overexpression in human erb-B-3 transgenic mice is enhanced by methylnitrosourea. 12483526

2002