Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.400 GeneticVariation LHGDN GSTM1 polymorphisms are associated with lung cancer risk in Asian smokers. 18463401

2008

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.400 GeneticVariation LHGDN we found evidence of an association between the CYP1A1 variant and GSTM1 null genotypes and increased risk of lung cancer. 17900751

2008

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.400 GeneticVariation LHGDN different combinations of GSTP1, GSTM1 and GSTT1 polymorphisms do not greatly increase risk of lung cancer 18415801

2008

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.400 GeneticVariation LHGDN Finding suggest of an association between 7-methylguanine excretion and lung cancer risk mainly among current smokers and subjects with GSTM1 null genotype. 17565746

2007

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.400 GeneticVariation LHGDN Role of the metabolic gene polymorphisms in non-smoker lung cancer patients from the International Collaborative Study on Genetic Susceptibility to Environmental Carcinogens. 16009381

2006

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.400 GeneticVariation LHGDN Our study suggests the importance of combined CYP1A1, GSTM1 and GSTT1 polymorphisms in the development of smoking-induced lung cancer. 16228113

2006

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.400 GeneticVariation LHGDN Relative lung cancer risk for the combined 2A/null GSTM1 genotypes was 2.51, which increased with the smoking. 16012082

2005

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.400 GeneticVariation LHGDN The estimated lung cancer risk for GSTM1 null, GSTP1 Ile/Val and GSTP1 Val/Val combined genotype was 1.44, implying no effect on lung cancer predisposition. 14628089

2004

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.400 GeneticVariation LHGDN The GSTM1-null genotype, which confers susceptibility to lung cancer, was associated with shorter survival. 12814998

2004

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.400 GeneticVariation LHGDN specific genotype combinations of CYP1A1, GSTM1 and GSTT1 alleles in the development of lung cancer in heavy smokers 14534704

2004

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.400 Biomarker LHGDN GSTM1 gene is implicated in genetic susceptibility to lung cancer among African American smokers 15008663

2004

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.400 Biomarker LHGDN The absence of the GSTM1 gene is implicated in susceptibility to lung cancer. 14666648

2003

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.400 GeneticVariation LHGDN study the null GSTM1 genotype is an independent risk factor for the development of lung cancer for Turkish population. 14553946

2003

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.400 AlteredExpression LHGDN Glutathione S-transferase mu (GST mu) enzyme detoxifies carcinogens in tobacco smoke/enzyme positivity rate of the lung cancer patient group (39%) was significantly lower than the control group. 11939169

2002

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.400 GeneticVariation LHGDN effects of glutathione S-transferase M1 polymorphisms and smoking on lung cancer risk 12151353

2002

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.400 Biomarker LHGDN Genetic determinants of lung cancer short-term survival: the role of glutathione-related genes 11844594

2002

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.400 GeneticVariation LHGDN association between carcinogen-DNA damage, enzyme genotypes and risk of lung cancer 12376472

2002

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.400 GeneticVariation LHGDN The deficient genotypes for GSTM1 and GSTP1 seem thus to be important risk modifiers for lung cancer, especially in combination. 12189190

2002