Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10855
Gene Symbol: HPSE
HPSE
CUI: C0025202
Disease: melanoma
melanoma 		0.400 AlteredExpression LHGDN Atypical melanocytes and melanoma cells expressed heparanase, VEGF and VEGFR-2. 18288398

2008
Entrez Id: 10855
Gene Symbol: HPSE
HPSE
CUI: C0025202
Disease: melanoma
melanoma 		0.400 AlteredExpression LHGDN Heparanase mechanisms of melanoma metastasis to the brain: Development and use of a brain slice model. 16288472

2006
Entrez Id: 10855
Gene Symbol: HPSE
HPSE
CUI: C0025202
Disease: melanoma
melanoma 		0.400 Biomarker LHGDN Elevated HPSE expression contributes to melanoma progression; however, further augmentation of HPSE presence can inhibit tumorigenicity. 16867222

2006
Entrez Id: 10855
Gene Symbol: HPSE
HPSE
CUI: C0025202
Disease: melanoma
melanoma 		0.400 Biomarker LHGDN Our results provide evidence demonstrating that HPSE-1 likely plays important roles in regulating the in vivo growth and progression of melanoma. 15645118

2005
Entrez Id: 10855
Gene Symbol: HPSE
HPSE
CUI: C0025202
Disease: melanoma
melanoma 		0.400 AlteredExpression LHGDN Restoration of HPSE-1 expression and functionality following Ad-S/hep infection of KCREB-transfected 70W cells recovered melanoma cell invasiveness. 15368349

2004