Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0025202
Disease: melanoma
melanoma
0.400 AlteredExpression LHGDN Therefore, we investigated the effects of vitamin C on the proliferation of melanoma cells via the modulation of COX-2 expression and IGF-I axis. 18297687

2008

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0025202
Disease: melanoma
melanoma
0.400 Biomarker LHGDN Complete and long-lasting regression of disseminated multiple skin melanoma metastases under treatment with cyclooxygenase-2 inhibitor. 16718274

2006

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0025202
Disease: melanoma
melanoma
0.400 AlteredExpression LHGDN Collectively, our data indicate that changes in the expression level of COX-2 are correlated with the development and progression of human melanoma, and imply that the COX-2 protein may be considered a potential prognostic and predictive marker in malignant melanoma. 16432453

2006

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0025202
Disease: melanoma
melanoma
0.400 Biomarker LHGDN Cyclooxygenase-2 inhibition and regression of metastatic melanoma. 17013098

2006

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0025202
Disease: melanoma
melanoma
0.400 Biomarker LHGDN Prognostic significance of cyclooxygenase-2 in oropharyngeal squamous cell carcinoma. 15014019

2004

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0025202
Disease: melanoma
melanoma
0.400 AlteredExpression LHGDN This study showed that mixed-cell tumours, representing the majority of uveal melanomas, may be further subclassified according to COX-2 expression, which serves as a marker of poor prognosis. 12956275

2003