Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker LHGDN A prostatic intraepithelial neoplasia-dependent p27 Kip1 checkpoint induces senescence and inhibits cell proliferation and cancer progression. 18691549

2008

Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker LHGDN Downregulation of both p21/Cip1 and p27/Kip1 produces a more aggressive prostate cancer phenotype. 18583941

2008

Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 GeneticVariation LHGDN CDKN1B V109G polymorphism frequency and prostate cancer risk in Taiwan. 18645269

2008

Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 AlteredExpression LHGDN A molecularly genetic determination of prognostic factors of the prostate cancer and their relationships to expression of protein p27kip1. 17319789

2007

Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 AlteredExpression LHGDN Down-regulation of p27(Kip 1) cyclin-dependent kinase inhibitor in prostate cancer: distinct expression in various prostate cells associating with tumor stage and grades. 17404436

2007

Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker LHGDN p27(kip1) and Ki-67 (MIB1) immunohistochemical expression in radical prostatectomy specimens of patients with clinically localized prostate cancer. 16097446

2005

Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 AlteredExpression LHGDN The progression of LNCaP human prostate cancer cells to androgen independence involves decreased FOXO3a expression and reduced p27KIP1 promoter transactivation. 15798096

2005

Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 GeneticVariation LHGDN A polymorphism in the CDKN1B gene is associated with increased risk of hereditary prostate cancer. 15026335

2004

Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 GeneticVariation LHGDN CDKN1A and CDKN1B polymorphisms and risk of advanced prostate carcinoma. 12727815

2003

Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker LHGDN The F-box protein SKP2 mediates androgen control of p27 stability in LNCaP human prostate cancer cells. 12188931

2002

Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 AlteredExpression LHGDN Elevated Skp2 protein expression in human prostate cancer: association with loss of the cyclin-dependent kinase inhibitor p27 and PTEN and with reduced recurrence-free survival. 12429629

2002