Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 GeneticVariation LHGDN Our aim was to determine the frequency of KLF6 and TP53 mutations in a well-defined group of prostate tumors with different stages and Gleason grades. 19020536

2008

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 GeneticVariation LHGDN Clinical significance of p53 alterations in surgically treated prostate cancers. 18552821

2008

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 GeneticVariation LHGDN TP53 mutation in prostate needle biopsies--comparison with patients follow-up. 18225585

2008

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 GeneticVariation LHGDN Paclitaxel enhanced radiation sensitization for the suppression of human prostate cancer tumor growth via a p53 independent pathway. 17823933

2007

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 AlteredExpression LHGDN Theaflavins induced apoptosis of LNCaP cells is mediated through induction of p53, down-regulation of NF-kappa B and mitogen-activated protein kinases pathways. 17499812

2007

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 AlteredExpression LHGDN Expression of androgen receptor is negatively regulated by p53. 18084622

2007

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker LHGDN Prostate derived factor in human prostate cancer cells: gene induction by vitamin D via a p53-dependent mechanism and inhibition of prostate cancer cell growth. 16741990

2006

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 GeneticVariation LHGDN Unique substitution of CHEK2 and TP53 mutations implicated in primary prostate tumors and cancer cell lines. 16941491

2006

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 GeneticVariation LHGDN Joint effect among p53, CYP1A1, GSTM1 polymorphism combinations and smoking on prostate cancer risk: an exploratory genotype-environment interaction study. 16625286

2006

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 AlteredExpression LHGDN Cyclooxygenase-2 suppresses hypoxia-induced apoptosis via a combination of direct and indirect inhibition of p53 activity in a human prostate cancer cell line. 15550400

2005

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 GeneticVariation LHGDN A p53 codon 72 polymorphism associated with prostate cancer development and progression in Japanese. 12824702

2004

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker LHGDN A significant fraction of prostate tumors with focally positive immunostaining for p53 have been confirmed to contain mutations in the p53 gene. 14663467

2003

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker LHGDN Androgen and the blocking of radiation-induced sensitization to Fas-mediated apoptosis through c-jun induction in prostate cancer cells. 12963547

2003