Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 AlteredExpression LHGDN The NMD mRNA surveillance pathway downregulates aberrant E-cadherin transcripts in gastric cancer cells and in CDH1 mutation carriers. 18427545

2008

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 Biomarker LHGDN Positive association of up-regulated Cripto-1 and down-regulated E-cadherin with tumour progression and poor prognosis in gastric cancer. 18312357

2008

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 GeneticVariation LHGDN A novel diffuse gastric cancer susceptibility variant in E-cadherin (CDH1) intron 2: a case control study in an Italian population. 18482459

2008

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 GeneticVariation LHGDN Hereditary diffuse gastric cancer: association with lobular breast cancer. 18046629

2008

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 AlteredExpression LHGDN Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells. 18377425

2008

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 GeneticVariation LHGDN Founder and recurrent CDH1 mutations in families with hereditary diffuse gastric cancer. 17545690

2007

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 GeneticVariation LHGDN Association between CDH1 haplotypes and gastric cancer risk in a Japanese population. 17852867

2007

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 GeneticVariation LHGDN Single nucleotide polymorphisms in the promoter region of the E-cadherin gene in gastric cancer: case-control study in a young Mexican population. 17549573

2007

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 Biomarker LHGDN Association of extracellular cleavage of E-cadherin mediated by MMP-7 with HGF-induced in vitro invasion in human stomach cancer cells. 17396032

2007

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 GeneticVariation LHGDN E-cadherin and hereditary diffuse gastric cancer. 17981184

2007

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 GeneticVariation LHGDN Germline E-cadherin mutations in familial lobular breast cancer. 17660459

2007

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 GeneticVariation LHGDN Hereditary diffuse gastric cancer and E-cadherin: description of the first germline mutation in an Italian family. 17126523

2007

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 GeneticVariation LHGDN Identification of seven novel germline mutations in the human E-cadherin (CDH1) gene. 17221870

2007

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 GeneticVariation LHGDN A novel mutation in the E-cadherin gene in the first family with hereditary diffuse gastric cancer reported in Spain. 16870389

2006

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 GeneticVariation LHGDN CDH1/E-cadherin germline mutations in early-onset gastric cancer. 16801346

2006

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 Biomarker LHGDN Frequent loss of membranous E-cadherin in gastric cancers: A cross-talk with Wnt in determining the fate of beta-catenin. 16132582

2005

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 GeneticVariation LHGDN Characterization of a recurrent germ line mutation of the E-cadherin gene: implications for genetic testing and clinical management. 16061854

2005

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 GeneticVariation LHGDN CDH1 associated gastric cancer: a report of a family and review of the literature. 15780560

2005

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 Biomarker LHGDN Clinical significance of dysadherin expression in gastric cancer patients. 15102690

2004

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 GeneticVariation LHGDN Germline E-cadherin mutations in hereditary diffuse gastric cancer: assessment of 42 new families and review of genetic screening criteria. 15235021

2004

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 PosttranslationalModification LHGDN Prognostic analysis of E-cadherin gene promoter hypermethylation in patients with surgically resected, node-positive, diffuse gastric cancer. 15102685

2004

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 GeneticVariation LHGDN Association of CDH1 haplotypes with susceptibility to sporadic diffuse gastric cancer. 12444556

2002

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 GeneticVariation LHGDN E-cadherin gene variants in gastric cancer families whose probands are diagnosed with diffuse gastric cancer. 12216071

2002