×
Entrez Id:
207
Gene Symbol:
AKT1
AKT1
Mammary Neoplasms
0.400
AlteredExpression
LHGDN
Mel-18 negatively regulates INK4a/ARF-independent cell cycle progression via Akt inactivation in breast cancer.
18519679
2008
×
Entrez Id:
207
Gene Symbol:
AKT1
AKT1
Mammary Neoplasms
0.400
Biomarker
LHGDN
Transforming growth factor beta engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumab.
18625725
2008
×
Entrez Id:
207
Gene Symbol:
AKT1
AKT1
Mammary Neoplasms
0.400
AlteredExpression
LHGDN
Clinical significance of Akt and HER2/neu overexpression in African-American and Latina women with breast cancer.
18184439
2008
×
Entrez Id:
207
Gene Symbol:
AKT1
AKT1
Mammary Neoplasms
0.400
AlteredExpression
LHGDN
Protein kinase C epsilon confers resistance of MCF-7 cells to TRAIL by Akt-dependent activation of Hdm2 and downregulation of p53.
18317451
2008
×
Entrez Id:
207
Gene Symbol:
AKT1
AKT1
Mammary Neoplasms
0.400
Biomarker
LHGDN
Associations between Notch-2, Akt-1 and HER2/neu expression in invasive human breast cancer: a tissue microarray immunophenotypic analysis on 98 patients.
18087195
2007
×
Entrez Id:
207
Gene Symbol:
AKT1
AKT1
Mammary Neoplasms
0.400
AlteredExpression
LHGDN
Abrogation of p53 by its antisense in MCF-7 breast carcinoma cells increases cyclin D1 via activation of Akt and promotion of cell proliferation.
17935714
2007
×
Entrez Id:
207
Gene Symbol:
AKT1
AKT1
Mammary Neoplasms
0.400
AlteredExpression
LHGDN
IGF-1 activates hEAG K(+) channels through an Akt-dependent signaling pathway in breast cancer cells: role in cell proliferation.
17520698
2007
×
Entrez Id:
207
Gene Symbol:
AKT1
AKT1
Mammary Neoplasms
0.400
AlteredExpression
LHGDN
HER-2/neu transcriptionally activates Jab1 expression via the AKT/beta-catenin pathway in breast cancer cells.
17914096
2007
×
Entrez Id:
207
Gene Symbol:
AKT1
AKT1
Mammary Neoplasms
0.400
AlteredExpression
LHGDN
p38MAPK-activated AKT in HER-2 overexpressing human breast cancer cells acts as an EGF-independent survival signal.
17612563
2007
×
Entrez Id:
207
Gene Symbol:
AKT1
AKT1
Mammary Neoplasms
0.400
Biomarker
LHGDN
Resveratrol-induced cell inhibition of growth and apoptosis in MCF7 human breast cancer cells are associated with modulation of phosphorylated Akt and caspase-9.
17299206
2006
×
Entrez Id:
207
Gene Symbol:
AKT1
AKT1
Mammary Neoplasms
0.400
AlteredExpression
LHGDN
Mechanism of Akt1 inhibition of breast cancer cell invasion reveals a protumorigenic role for TSC2.
16537497
2006
×
Entrez Id:
207
Gene Symbol:
AKT1
AKT1
Mammary Neoplasms
0.400
AlteredExpression
LHGDN
AKT regulation of estrogen receptor beta transcriptional activity in breast cancer.
16951146
2006
×
Entrez Id:
207
Gene Symbol:
AKT1
AKT1
Mammary Neoplasms
0.400
Biomarker
LHGDN
Regulated association of protein kinase B/Akt with breast tumor kinase.
15539407
2005
×
Entrez Id:
207
Gene Symbol:
AKT1
AKT1
Mammary Neoplasms
0.400
Biomarker
LHGDN
Increased level of phosphorylated akt measured by chemiluminescence-linked immunosorbent assay is a predictor of poor prognosis in primary breast cancer overexpressing ErbB-2.
15987444
2005
×
Entrez Id:
207
Gene Symbol:
AKT1
AKT1
Mammary Neoplasms
0.400
AlteredExpression
LHGDN
Akt phosphorylates the Y-box binding protein 1 at Ser102 located in the cold shock domain and affects the anchorage-independent growth of breast cancer cells.
15806160
2005
×
Entrez Id:
207
Gene Symbol:
AKT1
AKT1
Mammary Neoplasms
0.400
AlteredExpression
LHGDN
HER2/neu uses Akt to suppress retinoic acid response element binding activity in MDA-MB-453 breast cancer cells.
14612949
2003
×
Entrez Id:
207
Gene Symbol:
AKT1
AKT1
Mammary Neoplasms
0.400
AlteredExpression
LHGDN
PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest.
12244302
2002
×
Entrez Id:
207
Gene Symbol:
AKT1
AKT1
Mammary Neoplasms
0.400
PosttranslationalModification
LHGDN
Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer.
12244303
2002