×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Mammary Neoplasms
0.500
AlteredExpression
LHGDN
Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair.
18066063
2008
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors.
18332865
2008
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression.
18787170
2008
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Mammary Neoplasms
0.500
Biomarker
LHGDN
IGF-II and IGFBP-2 differentially regulate PTEN in human breast cancer cells.
17369847
2007
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Mammary Neoplasms
0.500
PosttranslationalModification
LHGDN
PIK3CA and PTEN mutations in adenoid cystic carcinoma of the breast metastatic to kidney.
17669465
2007
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Mammary Neoplasms
0.500
Biomarker
LHGDN
A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer.
17936563
2007
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Mammary Neoplasms
0.500
AlteredExpression
LHGDN
PTEN regulates phospholipase D and phospholipase C.
17405772
2007
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Mammary Neoplasms
0.500
AlteredExpression
LHGDN
Investigate the role of PTEN in chemotaxis of human breast cancer cells.
17761400
2007
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Mammary Neoplasms
0.500
Biomarker
LHGDN
Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance.
17911267
2007
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Mammary Neoplasms
0.500
AlteredExpression
LHGDN
Differential expression of novel naturally occurring splice variants of PTEN and their functional consequences in Cowden syndrome and sporadic breast cancer.
16436456
2006
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Mammary Neoplasms
0.500
Biomarker
LHGDN
Nuclear localization of PTEN is regulated by Ca(2+) through a tyrosil phosphorylation-independent conformational modification in major vault protein.
17178862
2006
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Mammary Neoplasms
0.500
AlteredExpression
LHGDN
Reduced expression of PTEN protein and its prognostic implications in invasive ductal carcinoma of the breast.
16020969
2005
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Mammary Neoplasms
0.500
PosttranslationalModification
LHGDN
Promoter methylation of the PTEN gene is a common molecular change in breast cancer.
15287024
2004
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Mammary Neoplasms
0.500
Biomarker
LHGDN
Dysregulated PTEN-PKB and negative receptor status in human breast cancer.
12569575
2003