Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C3714514
Disease: Infection
Infection
0.100 Biomarker LHGDN TGF-beta1 and SMAD3 may be involved in the pathology of corneal diseases associated with herpes simplex virus type 1 infection. 18776948

2008

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C3714514
Disease: Infection
Infection
0.100 Biomarker LHGDN The role of multinucleated giant cells may thus be different from epithelioid cells by virtue of higher MPT64, more TGF-beta, and reduced caspase 3 which may contribute towards persistence of infection. 18266005

2008

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN TGF-beta and IL-10 redundantly suppress hepatic inflammation during acute S.mansoni infection while intestinal inflammation is regulated by alternatively activated macrophages. 18981143

2008

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C3714514
Disease: Infection
Infection
0.100 GeneticVariation LHGDN TGF beta 1 polymorphisms (C allele at - 509C > T, T allele at codon10 T > C) contribute to progression of hepatic fibrosis in Chinese with hepatitis B virus infection. 18547814

2008

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C3714514
Disease: Infection
Infection
0.100 Biomarker LHGDN TGF-beta1 may play a dual role in HBV infection, in the suppression of immune responses against viral infection and in the direct inhibition of viral replication, resulting in minimization of liver damage in patients with chronic hepatitis. 17580335

2007

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C3714514
Disease: Infection
Infection
0.100 Biomarker LHGDN the TGF-beta-inducing protein of H.pylori might mediate the immune response and contribute to the pathogenesis of H.pylori infection 17922404

2007

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C3714514
Disease: Infection
Infection
0.100 Biomarker LHGDN Chronic inflammation associated with hepatitis C virus infection shifts hepatocytic TGF-beta signaling from tumor-suppression to fibrogenesis, accelerating liver fibrosis and increasing risk for hepatocarcinoma. 17596875

2007

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN TGFbeta expression is induced by rhinovirus infection in respiratory epithelial cells 17151785

2006

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C3714514
Disease: Infection
Infection
0.100 GeneticVariation LHGDN the genetic polymorphism in codon 10 of the TGF-beta1 gene may play a role in hepatocellular carcinoma development in patients with chronic hepatitis B infection. 15763337

2005

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN induced by R5 HIV-1 infection of fetal thymic organ culture (FOTC) which in turn induced CCR5 expression 15596839

2005

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN transcription upregulated directly by Hepatitis C virus core protein in parenchymal cells and suggests a new paradigm for exacerbation of liver fibrosis by HCV infection 14635011

2004

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C3714514
Disease: Infection
Infection
0.100 AlteredExpression LHGDN chronic active Epstein-Barr virus infection T-cells are activated to transcribe IFN gamma, IL-10, and TGF beta excessively, and the latter two genes are expressed preferentially in the EBV-infected subsets 15368517

2004