Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 102724652
Gene Symbol: CRYAA2
CRYAA2
CUI: C0009691
Disease: Congenital cataract
Congenital cataract
0.200 Biomarker MGD AlphaA-crystallin R49Cneo mutation influences the architecture of lens fiber cell membranes and causes posterior and nuclear cataracts in mice. 19619312

2009

Entrez Id: 102724652
Gene Symbol: CRYAA2
CRYAA2
CUI: C0009691
Disease: Congenital cataract
Congenital cataract
0.200 Biomarker MGD Mechanism of small heat shock protein function in vivo: a knock-in mouse model demonstrates that the R49C mutation in alpha A-crystallin enhances protein insolubility and cell death. 18056999

2008

Entrez Id: 102724652
Gene Symbol: CRYAA2
CRYAA2
CUI: C0009691
Disease: Congenital cataract
Congenital cataract
0.200 Biomarker MGD Reduced survival of lens epithelial cells in the alphaA-crystallin-knockout mouse. 12584250

2003

Entrez Id: 102724652
Gene Symbol: CRYAA2
CRYAA2
CUI: C0009691
Disease: Congenital cataract
Congenital cataract
0.200 Biomarker MGD Characterization of a new, dominant V124E mutation in the mouse alphaA-crystallin-encoding gene. 11687536

2001

Entrez Id: 102724652
Gene Symbol: CRYAA2
CRYAA2
CUI: C0009691
Disease: Congenital cataract
Congenital cataract
0.200 Biomarker MGD Targeted disruption of the mouse alpha A-crystallin gene induces cataract and cytoplasmic inclusion bodies containing the small heat shock protein alpha B-crystallin. 9023351

1997

Entrez Id: 102724652
Gene Symbol: CRYAA2
CRYAA2
CUI: C0009691
Disease: Congenital cataract
Congenital cataract
0.200 Biomarker MGD Chromosomal localization of a new mouse lens opacity gene (lop18) 8812430

1996