×
Entrez Id:
3952
Gene Symbol:
LEP
LEP
Obesity
0.700
Biomarker
MGD
BBS-induced ciliary defect enhances adipogenesis, causing paradoxical higher-insulin sensitivity, glucose usage, and decreased inflammatory response.
22958920
2012
×
Entrez Id:
3952
Gene Symbol:
LEP
LEP
Obesity
0.700
Biomarker
MGD
BTBR Ob/Ob mutant mice model progressive diabetic nephropathy.
20634301
2010
×
Entrez Id:
3952
Gene Symbol:
LEP
LEP
Obesity
0.700
Biomarker
MGD
Morphological and biochemical alterations of skeletal muscles from the genetically obese (ob/ob) mouse.
19528970
2009
×
Entrez Id:
3952
Gene Symbol:
LEP
LEP
Obesity
0.700
Biomarker
MGD
Leptin derived from adipocytes in injured peripheral nerves facilitates development of neuropathic pain via macrophage stimulation.
19620723
2009
×
Entrez Id:
3952
Gene Symbol:
LEP
LEP
Obesity
0.700
Biomarker
MGD
The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity.
19103808
2008
×
Entrez Id:
3952
Gene Symbol:
LEP
LEP
Obesity
0.700
Biomarker
MGD
A role for brain-specific homeobox factor Bsx in the control of hyperphagia and locomotory behavior.
17550780
2007
×
Entrez Id:
3952
Gene Symbol:
LEP
LEP
Obesity
0.700
Biomarker
MGD
Deficiency of adiponectin receptor 2 reduces diet-induced insulin resistance but promotes type 2 diabetes.
17068142
2007
×
Entrez Id:
3952
Gene Symbol:
LEP
LEP
Obesity
0.700
Biomarker
MGD
Increased pulmonary responses to acute ozone exposure in obese db/db mice.
16373670
2006
×
Entrez Id:
3952
Gene Symbol:
LEP
LEP
Obesity
0.700
Biomarker
MGD
Leptin is required for uncoupling protein-1-independent thermogenesis during cold stress.
16469807
2006
×
Entrez Id:
3952
Gene Symbol:
LEP
LEP
Obesity
0.700
Biomarker
MGD
Leptin is a circulating hormone and major adiposity signal involved in long-term energy homeostasis.
16293682
2006
×
Entrez Id:
3952
Gene Symbol:
LEP
LEP
Obesity
0.700
Biomarker
MGD
Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists.
16326714
2006
×
Entrez Id:
3952
Gene Symbol:
LEP
LEP
Obesity
0.700
Biomarker
MGD
Cardiac contractile dysfunction in Lep/Lep obesity is accompanied by NADPH oxidase activation, oxidative modification of sarco(endo)plasmic reticulum Ca2+-ATPase and myosin heavy chain isozyme switch.
16612592
2006
×
Entrez Id:
3952
Gene Symbol:
LEP
LEP
Obesity
0.700
Biomarker
MGD
Severe pulmonary metastasis in obese and diabetic mice.
16998795
2006
×
Entrez Id:
3952
Gene Symbol:
LEP
LEP
Obesity
0.700
Biomarker
MGD
Impaired cardiac contractile function in ventricular myocytes from leptin-deficient ob/ob obese mice.
16394172
2006
×
Entrez Id:
3952
Gene Symbol:
LEP
LEP
Obesity
0.700
Biomarker
MGD
Disruption of leptin signaling contributes to cardiac hypertrophy independently of body weight in mice.
12885755
2003
×
Entrez Id:
3952
Gene Symbol:
LEP
LEP
Obesity
0.700
Biomarker
MGD
Leptin -deficient mice of the DBA-ob strain have variable obesity -diabetes.
12136396
2002
×
Entrez Id:
3952
Gene Symbol:
LEP
LEP
Obesity
0.700
Biomarker
MGD
Genetic obesity unmasks nonlinear interactions between murine type 2 diabetes susceptibility loci.
11078464
2000
×
Entrez Id:
3952
Gene Symbol:
LEP
LEP
Obesity
0.700
Biomarker
MGD
Early treatment of obese (ob/ob) mice with triiodothyronine increases oxidative metabolism in muscle but not in brown adipose tissue or liver.
7815168
1995
×
Entrez Id:
3952
Gene Symbol:
LEP
LEP
Obesity
0.700
Biomarker
MGD
Recombinant ob protein reduces feeding and body weight in the ob/ob mouse.
7560100
1995
×
Entrez Id:
3952
Gene Symbol:
LEP
LEP
Obesity
0.700
Biomarker
MGD
Characterization of plasma lipids in genetically obese mice: the mutants obese, diabetes, fat, tubby, and lethal yellow.
8177042
1994
×
Entrez Id:
3952
Gene Symbol:
LEP
LEP
Obesity
0.700
Biomarker
MGD
Early treatment of obese (ob/ob) mice with triiodothyronine increases oxygen consumption and temperature and decreases body fat content.
7800681
1994
×
Entrez Id:
3952
Gene Symbol:
LEP
LEP
Obesity
0.700
Biomarker
MGD
Diminished epinephrine excretion in genetically obese (ob/ob) mice and monosodium glutamate-treated rats.
1382044
1992
×
Entrez Id:
3952
Gene Symbol:
LEP
LEP
Obesity
0.700
Biomarker
MGD
The influence of genetic background on the expression of the obese (Ob) gene in the mouse.
4588246
1973