DisGeNET - a database of gene-disease associations

Source: MGD

Disease: Sensorineural hearing loss, bilateral ×

Gene: MYO6 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	4646
Gene Symbol:	MYO6

MYO6

CUI:	C0452138
Disease:	Sensorineural hearing loss, bilateral

Sensorineural hearing loss, bilateral

0.300

Biomarker

MGD

Myosin VI is required for normal retinal function.

15978262

2005

Entrez Id:	4646
Gene Symbol:	MYO6

MYO6

CUI:	C0452138
Disease:	Sensorineural hearing loss, bilateral

Sensorineural hearing loss, bilateral

0.300

Biomarker

MGD

Myo15 function is distinct from Myo6, Myo7a and pirouette genes in development of cochlear stereocilia.

12966030

2003

Entrez Id:	4646
Gene Symbol:	MYO6

MYO6

CUI:	C0452138
Disease:	Sensorineural hearing loss, bilateral

Sensorineural hearing loss, bilateral

0.300

Biomarker

MGD

Role of myosin VI in the differentiation of cochlear hair cells.

10525338

1999

Entrez Id:	4646
Gene Symbol:	MYO6

MYO6

CUI:	C0452138
Disease:	Sensorineural hearing loss, bilateral

Sensorineural hearing loss, bilateral

0.300

Biomarker

MGD

The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells.

7493015

1995