DisGeNET - a database of gene-disease associations

Source: MGD

Disease: Sensorineural hearing loss, bilateral ×

Gene: S1PR2 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	9294
Gene Symbol:	S1PR2

S1PR2

CUI:	C0452138
Disease:	Sensorineural hearing loss, bilateral

Sensorineural hearing loss, bilateral

0.200

Biomarker

MGD

S1PR2 variants associated with auditory function in humans and endocochlear potential decline in mouse.

27383011

2016

Entrez Id:	9294
Gene Symbol:	S1PR2

S1PR2

CUI:	C0452138
Disease:	Sensorineural hearing loss, bilateral

Sensorineural hearing loss, bilateral

0.200

Biomarker

MGD

Autosomal-Recessive Hearing Impairment Due to Rare Missense Variants within S1PR2.

26805784

2016

Entrez Id:	9294
Gene Symbol:	S1PR2

S1PR2

CUI:	C0452138
Disease:	Sensorineural hearing loss, bilateral

Sensorineural hearing loss, bilateral

0.200

Biomarker

MGD

The S1P2 sphingosine 1-phosphate receptor is essential for auditory and vestibular function.

16945494

2006