Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7068
Gene Symbol: THRB
THRB
CUI: C2940786
Disease: Thyroid Hormone Resistance Syndrome
Thyroid Hormone Resistance Syndrome
0.900 Biomarker MGD A thyroid hormone receptor mutation that dissociates thyroid hormone regulation of gene expression in vivo. 19439650

2009

Entrez Id: 7068
Gene Symbol: THRB
THRB
CUI: C2940786
Disease: Thyroid Hormone Resistance Syndrome
Thyroid Hormone Resistance Syndrome
0.900 Biomarker MGD Hyperactivity, impaired learning on a vigilance task, and a differential response to methylphenidate in the TRbetaPV knock-in mouse. 15983791

2005

Entrez Id: 7068
Gene Symbol: THRB
THRB
CUI: C2940786
Disease: Thyroid Hormone Resistance Syndrome
Thyroid Hormone Resistance Syndrome
0.900 Biomarker MGD Contrasting skeletal phenotypes in mice with an identical mutation targeted to thyroid hormone receptor alpha1 or beta. 16051666

2005

Entrez Id: 7068
Gene Symbol: THRB
THRB
CUI: C2940786
Disease: Thyroid Hormone Resistance Syndrome
Thyroid Hormone Resistance Syndrome
0.900 Biomarker MGD Thyroid hormone action in the absence of thyroid hormone receptor DNA-binding in vivo. 12925699

2003

Entrez Id: 7068
Gene Symbol: THRB
THRB
CUI: C2940786
Disease: Thyroid Hormone Resistance Syndrome
Thyroid Hormone Resistance Syndrome
0.900 Biomarker MGD A thyrotoxic skeletal phenotype of advanced bone formation in mice with resistance to thyroid hormone. 12677005

2003

Entrez Id: 7068
Gene Symbol: THRB
THRB
CUI: C2940786
Disease: Thyroid Hormone Resistance Syndrome
Thyroid Hormone Resistance Syndrome
0.900 Biomarker MGD Knock-in mouse model for resistance to thyroid hormone (RTH): an RTH mutation in the thyroid hormone receptor beta gene disrupts cochlear morphogenesis. 12382103

2002

Entrez Id: 7068
Gene Symbol: THRB
THRB
CUI: C2940786
Disease: Thyroid Hormone Resistance Syndrome
Thyroid Hormone Resistance Syndrome
0.900 Biomarker MGD Retardation of cochlear maturation and impaired hair cell function caused by deletion of all known thyroid hormone receptors. 11739587

2001

Entrez Id: 7068
Gene Symbol: THRB
THRB
CUI: C2940786
Disease: Thyroid Hormone Resistance Syndrome
Thyroid Hormone Resistance Syndrome
0.900 Biomarker MGD An unliganded thyroid hormone receptor causes severe neurological dysfunction. 11274423

2001

Entrez Id: 7068
Gene Symbol: THRB
THRB
CUI: C2940786
Disease: Thyroid Hormone Resistance Syndrome
Thyroid Hormone Resistance Syndrome
0.900 Biomarker MGD Mice with a targeted mutation in the thyroid hormone beta receptor gene exhibit impaired growth and resistance to thyroid hormone. 11069286

2000

Entrez Id: 7068
Gene Symbol: THRB
THRB
CUI: C2940786
Disease: Thyroid Hormone Resistance Syndrome
Thyroid Hormone Resistance Syndrome
0.900 Biomarker MGD Thyroid hormone receptor beta-dependent expression of a potassium conductance in inner hair cells at the onset of hearing. 9861043

1998

Entrez Id: 7068
Gene Symbol: THRB
THRB
CUI: C2940786
Disease: Thyroid Hormone Resistance Syndrome
Thyroid Hormone Resistance Syndrome
0.900 Biomarker MGD Recessive resistance to thyroid hormone in mice lacking thyroid hormone receptor beta: evidence for tissue-specific modulation of receptor function. 8670802

1996

Entrez Id: 7068
Gene Symbol: THRB
THRB
CUI: C2940786
Disease: Thyroid Hormone Resistance Syndrome
Thyroid Hormone Resistance Syndrome
0.900 Biomarker MGD Thyroid hormone receptor beta is essential for development of auditory function. 8673137

1996