Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.800 Biomarker PSYGENET Association of the T102C polymorphism in the HTR2A gene with major depressive disorder, bipolar disorder, and schizophrenia. 24962835

2014

Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.800 Biomarker PSYGENET Ongoing research has identified a region of the HTR2A promoter that has been associated with a number of medical outcomes in adults and infants, including bipolar disorder, schizophrenia, chronic fatigue syndrome, borderline personality disorder, suicidality, and neurobehavioral outcomes. 25043477

2014

Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.800 Biomarker PSYGENET We found that the association of the HTR2A -1438A/G polymorphism with SZ depends on the ethnic origin of the study population, and this genetic variant does not modify the susceptibility to BD or MDD.© 2013 Wiley Periodicals, Inc. 23404241

2013

Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.800 Biomarker PSYGENET Logistic regression analysis showed a significant effect of the ALDH2 and the 5-HT2A-A1438G polymorphisms, and a significant interaction effect for the A/G genotypes of the 5-HT2A-A1438G polymorphism and the ALDH2*1*1 genotypes (p=0.004) discriminated between bipolar-I patients and controls without bipolar disorder. 22564712

2012

Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.800 Biomarker PSYGENET Furthermore, epigenetic down-regulation of HTR2A was associated with early age of disease onset in SCZ and BD. 21550210

2011