Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6285
Gene Symbol: S100B
S100B
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.600 Biomarker PSYGENET Reversal of depressed behaviors in mice by p11 gene therapy in the nucleus accumbens. 20962330

2010

Entrez Id: 6285
Gene Symbol: S100B
S100B
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.600 Biomarker PSYGENET Significant differences in the subgroup depression (first-episode and recurrent depression) were also shown in 3 genotypes of S100B rs9722 and rs11911834 in patients and control subjects (P < 0.05). 19497163

2009

Entrez Id: 6285
Gene Symbol: S100B
S100B
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.600 Biomarker PSYGENET Although it may be open for discussion whether the neuroprotective effects of ONO-2506 are exclusively due to its inhibition of S100B synthesis, the latter action of ONO-2506 warrants studies of the effects of this drug in the pathobiology of depression. 16797859

2006

Entrez Id: 6285
Gene Symbol: S100B
S100B
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.600 Biomarker PSYGENET S100 beta, a calcium binding brain protein expressed by astrocytes, has been shown to be involved in higher neural processes, including hippocampal-dependent behavioral traits and hippocampal neuronal long-term potentiation (LTP) and depression (LTD), neurophysiological phenomena that may be involved in exploring, learning and remembering novel stimuli. 8804639

1996

Entrez Id: 6285
Gene Symbol: S100B
S100B
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.600 Biomarker PSYGENET S100 beta, a calcium binding astrocytic brain protein, influences hippocampal long-term potentiation (LTP) and depression (LTD), synaptic processes suggested to play role in spatial (contextual) learning and memory. 8840925

1996