Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3064
Gene Symbol: HTT
HTT
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.420 Biomarker PSYGENET In vivo, the ablation of Casp6 results in a partial rescue of body weight gain, normalized IGF-1 levels, a reversal of the depression-like phenotype and decreased HTT levels. 25583186

2015
Entrez Id: 3064
Gene Symbol: HTT
HTT
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.420 Biomarker PSYGENET In order to explore the biological origin of depression and anxiety in HD, we used a mouse model that expresses the human full-length mutant huntingtin, the BACHD mouse. 23697793

2013
Entrez Id: 3064
Gene Symbol: HTT
HTT
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.420 Biomarker PSYGENET These results support the notion that huntingtin participates in anxiety and depression-like behavior and is thus relevant to the etiology of mood disorders and anxiety/depression in HD. 23678106

2013
Entrez Id: 3064
Gene Symbol: HTT
HTT
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.420 Biomarker PSYGENET Apolipoprotein E genotypes do not influence the age of onset in Huntington's disease. 15548484

2004