Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5368
Gene Symbol: PNOC
PNOC
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.310 Biomarker PSYGENET Complete knockout of the nociceptin/orphanin FQ receptor in the rat does not induce compensatory changes in mu, delta and kappa opioid receptors. 19527777

2009
Entrez Id: 5368
Gene Symbol: PNOC
PNOC
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.310 Biomarker PSYGENET "Acute stress differentially affects corticotropin-releasing hormone mRNA expression in the central amygdala of the ""depressed"" flinders sensitive line and the control flinders resistant line rats." 18077069

2008
Entrez Id: 5368
Gene Symbol: PNOC
PNOC
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.310 Biomarker PSYGENET In an animal model of depression, Flinders Sensitive Line rats, and Sprague Dawley controls we analyzed if 7 weeks of social isolation of adult animals affect the number of newly proliferated cells in the dentate gyrus or mRNAs of Neuropeptide Y (NPY), the NPY-Y1 receptor, nociceptin, BDNF, and the serotonin 5HT1A and 5HT2A receptors, which are molecules involved in hippocampal plasticity. 17879375

2007