Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7054
Gene Symbol: TH
TH
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.320 Biomarker PSYGENET The results indicate that there exists possible interrelation between TH and TPH gene expression and epigenetic histone acetylation in CUS-induced depressive rats, which at least partly contributes to the etiology of depression. 24495952

2014

Entrez Id: 7054
Gene Symbol: TH
TH
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.320 Biomarker PSYGENET Tyrosine-hydroxylase (TH) and dopamine-beta-hydroxylase (DBH) mRNA levels were decreased both in right and left atria, while phenylethanolamine N-methyltransferase (PNMT) mRNAs were increased in left atria and both ventricles of depression model rats. 23305027

2012

Entrez Id: 7054
Gene Symbol: TH
TH
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.320 Biomarker PSYGENET We found that genotype Met/Met of the Val66Met polymorphism of the brain-derived neurotrophic factor gene was positively associated with depressive disorder (P < 0.05), but we were not able to find any significant associations of both the depressive disorder and metabolic syndrome with the remaining polymorphisms studied (methylenetetrahydrofolate reductase 677CT, methylenetet rahydrofolate reductase 1298AC, endothelial nitric oxide synthase Glu298Asp, and tyrosine hydroxylase). 20163778

2010

Entrez Id: 7054
Gene Symbol: TH
TH
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.320 Biomarker PSYGENET Elevated renal norepinephrine in proANP gene-disrupted mice is associated with increased tyrosine hydroxylase expression in sympathetic ganglia. 17482290

2007

Entrez Id: 7054
Gene Symbol: TH
TH
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.320 Biomarker PSYGENET Overexpressed thioredoxin compensates Fanconi anemia related chromosomal instability. 11948424

2002