Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.310 Biomarker PSYGENET We have assessed TNF(-/-), TNF-R1(-/-) and TNF-R2(-/-) mice against C57BL/6 wild-type (WT) mice from 12 weeks of age in order to evaluate measures of spatial memory and learning in the Barnes maze (BM) and Y-maze, as well as other behaviours such as exploration, social interaction, anxiety and depression-like behaviour in a battery of tests. 24094876

2014

Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.310 Biomarker PSYGENET Etanercept, a soluble TNF receptor, and TNFR1 deficiency protected against the depression in diaphragm-specific force caused by doxorubicin. 21097524

2011

Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.310 Biomarker PSYGENET The depression-like behavior was virtually abolished in TNF? p55 receptor-knockout mice, and increased B1 receptor mRNA expression was completely absent in this mouse strain. 21194425

2011

Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.310 Biomarker PSYGENET Circulating levels of interleukin-6 (IL-6), soluble IL-6 receptor (sIL-6R), tumor necrosis factor-alpha-receptor (TNF-RII), and soluble intercellular adhesion molecule (sICAM) did not differ between those with and without depression. 17094069

2007

Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.310 Biomarker PSYGENET We used a panel of behavioral assays to assess TNFR1(-/-) and TNFR2(-/-) mice for anxiety and depression-like behaviors. 16458261

2006