Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse 		0.740 Biomarker PSYGENET CYP2E1 gene promoter polymorphism -1293G>C increases the risk of essential hypertension in men with alcohol abuse. 24288753

2013
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse 		0.740 Biomarker PSYGENET Cytochrome P450 2E1 high activity polymorphism in alcohol abuse and end-organ disease. 16425414

2005
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse 		0.740 Biomarker PSYGENET Examination of a CYP2E1 repeat polymorphism in a monkey model of alcohol abuse. 11505041

2001
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse 		0.740 Biomarker PSYGENET To further investigate autoantibodies against cytochrome P-450s during alcohol abuse, sera of rats chronically treated with ethanol in the total enteral nutrition model and sera from alcoholics with or without alcohol liver disease and from control subjects were analyzed by enzyme-linked immunosorbent assay and Western blotting for the presence of IgG against rat and human CYP2E1, rat CYP3A1, and human CYP3A4. 9927612

1999
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse 		0.740 Biomarker PSYGENET The findings indicate that Caucasians carrying the Rsa I c2 allele of the CYP2E1 gene may be at higher risk of developing ALD if they abuse alcohol. 8747406

1995