Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1137
Gene Symbol: CHRNA4
CHRNA4
CUI: C0344315
Disease: Depressed mood
Depressed mood 		0.340 Biomarker PSYGENET Study findings identified a significant link between the CHRNA4:rs1044396 polymorphism and depression and loneliness in the aged. 22008229

2012
Entrez Id: 1137
Gene Symbol: CHRNA4
CHRNA4
CUI: C0344315
Disease: Depressed mood
Depressed mood 		0.340 Biomarker PSYGENET We identified a significant epistasis effect BCL1 by CHRNA4 showing that carriers of the CC genotype at the BCL1 locus who were also homozygous for the T allele at the CHRNA4 locus had the highest depression scores. 22760121

2012
Entrez Id: 1137
Gene Symbol: CHRNA4
CHRNA4
CUI: C0344315
Disease: Depressed mood
Depressed mood 		0.340 Biomarker PSYGENET Thus, we also briefly review data generated from genetically modified mice to support a role for discrete nAChR subunits in anxiety disorders, depression, and schizophrenia. 18690103

2008