Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.400 Biomarker PSYGENET In MDD, however, the effect of the val66met polymorphism is not detectable, possibly due to a ceiling effect of over-expression of 5-HT(1A) receptors in mood disorders. 24607934

2014
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.400 Biomarker PSYGENET RGS6 is enriched in hippocampal and cortical neurons, 5-HT(1A)R-expressing cells implicated in mood disorders. 24421401

2014
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.400 Biomarker PSYGENET Results from this expanded meta-analysis, which included our own new study, suggest that rs6295 (C-1019G) and rs878567 in HTR1A are related to the pathophysiology of MDs, with overlap between MDD and BP. 22752684

2013
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.400 Biomarker PSYGENET Altered regulation of the serotonin-1A (5-HT1A) receptor gene is implicated in major depression and mood disorders. 22232550

2012
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.400 Biomarker PSYGENET Due to its modulatory effect on serotonin (5-HT) release, the 5-HT(1A)-receptor is thought to play a decisive role in the therapy of this mood disorder. 21419787

2011