Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1312
Gene Symbol: COMT
COMT
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
0.520 Biomarker PSYGENET Several studies have looked for a link between cocaine addiction and the genes of the dopaminergic system: the genes DRD2, COMT, SLC6A3 (coding for the dopamine transporter DAT) and DBH (coding for the dopamine beta hydroxylase) but unfortunately very few well established results. 20801583

2010

Entrez Id: 1312
Gene Symbol: COMT
COMT
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
0.520 Biomarker PSYGENET In this issue of Neuropsychopharmacology, several studies are presented supporting a role for COMT as a factor in cocaine addiction, brain reward activation, response to tolcapone, distractibility in ADHD, and fMRI bold response. 18923401

2008

Entrez Id: 1312
Gene Symbol: COMT
COMT
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
0.520 Biomarker PSYGENET Results suggest that variation in COMT increases risk for cocaine dependence. 18704099

2008