Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1621
Gene Symbol: DBH
DBH
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
0.370 Biomarker PSYGENET The findings provide limited support for the efficacy of disulfiram for reducing cocaine use and suggest that its mechanism of action may involve inhibition of D?H. 24462581

2014

Entrez Id: 1621
Gene Symbol: DBH
DBH
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
0.370 Biomarker PSYGENET Disulfiram is a cocaine addiction pharmacotherapy that inhibits dopamine ?-hydroxylase (D?H) and reduces norepinephrine production. 23849431

2014

Entrez Id: 1621
Gene Symbol: DBH
DBH
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
0.370 Biomarker PSYGENET The influence of dopamine ?-hydroxylase gene polymorphism rs1611115 on levodopa/carbidopa treatment for cocaine dependence: a preliminary study. 24809448

2014

Entrez Id: 1621
Gene Symbol: DBH
DBH
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
0.370 Biomarker PSYGENET This study indicates that the DBH genotype of a patient could be used to identify a subset of individuals for which disulfiram treatment might be an effective pharmacotherapy for cocaine dependence. 22906516

2013

Entrez Id: 1621
Gene Symbol: DBH
DBH
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
0.370 Biomarker PSYGENET This study indicates that a patient's DBH genotype could be used to identify a subset of individuals for whom vaccine treatment may be an effective pharmacotherapy for cocaine dependence. 23458673

2013