Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
0.560 Biomarker PSYGENET Several studies have looked for a link between cocaine addiction and the genes of the dopaminergic system: the genes DRD2, COMT, SLC6A3 (coding for the dopamine transporter DAT) and DBH (coding for the dopamine beta hydroxylase) but unfortunately very few well established results. 20801583

2011

Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
0.560 Biomarker PSYGENET We genotyped the Int8 and 3'UTR variable number of tandem repeats of the dopamine transporter gene (DAT1/SLC6A3), the TaqIA (rs1800497) and TaqIB (rs1079597) SNP polymorphisms within the dopamine receptor D2 gene and the 19-bp insertion/deletion and c.444G>A (rs1108580) polymorphisms of the dopamine ?-hydroxylase gene (DBH) in a Spanish sample of 169 patients with cocaine addiction and 169 sex-matched controls. 20505554

2011

Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
0.560 Biomarker PSYGENET Methylphenidate treatment in adolescent rats with an attention deficit/hyperactivity disorder phenotype: cocaine addiction vulnerability and dopamine transporter function. 21150910

2011

Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
0.560 Biomarker PSYGENET Our study suggests that there is no association between the DRD2 and DAT1 polymorphisms and CD. 20170711

2010

Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
0.560 Biomarker PSYGENET Disulfiram and methylphenidate pharmacotherapies for cocaine addiction are optimized by considering polymorphisms affecting DbetaH and DAT1 respectively. 19462300

2009