Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2917
Gene Symbol: GRM7
GRM7
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.490 Biomarker PSYGENET We aimed to gather more evidence that rs2522833 is indeed the causal variant in the GAIN-MDD cohort or to find a previously undetected common variant in either PCLO, GRM7, or SLC6A4 with a higher association in this cohort. 24278217

2013

Entrez Id: 2917
Gene Symbol: GRM7
GRM7
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.490 Biomarker PSYGENET A meta-analysis of 3,957 case subjects with major depressive disorder and 3,428 control subjects from the Sequenced Treatment Alternatives to Relieve Depression (STAR*D), Genetics of Recurrent Early-onset Depression (GenRED), and the Genetic Association Information Network-MDD (GAIN-MDD) data sets demonstrated a region of association for major depressive disorder within GRM7. 21813496

2011

Entrez Id: 2917
Gene Symbol: GRM7
GRM7
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.490 Biomarker PSYGENET On the basis of previous biological evidence, we consider GRM7 a strong MDD candidate gene. 20038947

2011

Entrez Id: 2917
Gene Symbol: GRM7
GRM7
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.490 Biomarker PSYGENET There is increasing evidence to suggest that metabotropic glutamate (mGlu) receptors including mGlu(7) receptor are important in the pathophysiology of stress-related psychiatric disorders such as anxiety and major depression. mGlu(7) receptor is highly expressed in the hippocampus, a key region involved in the modulation of depression-related behaviour. 20638442

2010

Entrez Id: 2917
Gene Symbol: GRM7
GRM7
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.490 Biomarker PSYGENET These genes include GRM7, previously associated to major depression disorder and bipolar disorder, SLC6A13, in anxiety disorders, and S100B, SSTR5 and COMT in schizophrenia. 20398908

2010