Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5144
Gene Symbol: PDE4D
PDE4D
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.500 Biomarker RGD Consistent with other data on PDE4D deficiency, Pde4d KD rats showed depression resistance in the Porsolt forced swim test and hyperreactivity of the acoustic startle response with no differential response on prepulse inhibition, suggesting no sensorimotor gating defect. 22487514

2012

Entrez Id: 5144
Gene Symbol: PDE4D
PDE4D
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.500 Biomarker RGD The rat model confirms Pde4d's role in depression but not in spatial learning or memory enhancement and shows for the first time higher fear conditioning and altered extinction compared with controls. 22487514

2012