Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6550
Gene Symbol: SLC9A3
SLC9A3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.300 Biomarker RGD In ANG II-clamped rats, acute hypertension also provoked disappearance of NHE3 from the apical membranes (27 +/- 2% decrease of total), but NHE3 was shifted to membranes enriched in intermicrovillar cleft and dense apical tubules (step 1) rather than endosomal/lysosomal membranes (step 2). 12372791

2002
Entrez Id: 6550
Gene Symbol: SLC9A3
SLC9A3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.300 Biomarker RGD We conclude that the decrease in renal PT Na(+) transport during acute hypertension is mediated by removal of transport-competent NHE3 from the apical brush border to subapical and internal reserves. 11880335

2002