Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1910
Gene Symbol: EDNRB
EDNRB
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
0.500 Biomarker RGD The aldose reductase inhibitors sorbinil and zopolrestat mitigated endotoxin-induced pulmonary hypertension, ET-1 stimulation, and differential ET(B) receptor regulation. 18091567

2008

Entrez Id: 1910
Gene Symbol: EDNRB
EDNRB
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
0.500 Biomarker RGD Thus, an exaggerated response to MCT during ETB receptor blockade also seems to be mediated by ETA receptor activation, thereby suggesting that ETA receptor-mediated action is exclusively contributive to the pathogenesis of MCT-induced pulmonary hypertension, although we cannot rule out a protective role of ETB receptor-mediated action. 15243299

2004