Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
0.500 Therapeutic RGD Phenotypically Silent Bone Morphogenetic Protein Receptor 2 Mutations Predispose Rats to Inflammation-Induced Pulmonary Arterial Hypertension by Enhancing the Risk for Neointimal Transformation. 31462075

2019

Entrez Id: 240
Gene Symbol: ALOX5
ALOX5
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
0.500 Biomarker RGD These data suggest that 5-LO plays a critical role in the progression of pulmonary hypertension in rats and that the detrimental effect of 5-LO is manifest only in the setting of pulmonary vascular endothelial cell dysfunction. 14726295

2004

Entrez Id: 240
Gene Symbol: ALOX5
ALOX5
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
0.500 Biomarker RGD Our results support the hypothesis that the 5-LO is involved in lung vascular tone regulation and in the development of chronic pulmonary hypertension in hypoxic rodent models. 8647941

1996