Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0028754
Disease: Obesity
Obesity
0.700 Biomarker RGD Early development of podocyte injury independently of hyperglycemia and elevations in arterial pressure in nondiabetic obese Dahl SS leptin receptor mutant rats. 27465994

2016

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0028754
Disease: Obesity
Obesity
0.700 Biomarker RGD Endogenous leptin receptor signaling in the medial nucleus tractus solitarius affects meal size and potentiates intestinal satiation signals. 22693203

2012

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0028754
Disease: Obesity
Obesity
0.700 Biomarker RGD Nonsense mutation of leptin receptor in the obese spontaneously hypertensive Koletsky rat. 8841178

1996

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0028754
Disease: Obesity
Obesity
0.700 Biomarker RGD These facts suggest that the substitution at codon 269 of the OB-R cDNA represents the crucial mutation which results in the obese phenotype of Zucker (fa/fa) rat. 8702432

1996