×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Inherited Mutations in Women With Ovarian Carcinoma.
26720728 2016
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Structural basis for recruitment of BRCA2 by PALB2.
19609323 2009
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
The genetic landscape of high-risk neuroblastoma.
23334666 2013
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Prevalence of PALB2 mutations in Australasian multiple-case breast cancer families.
23448497 2013
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Germline mutations in BRIP1 and PALB2 in Jewish high cancer risk families.
22692731 2012
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Low prevalence of germline PALB2 mutations in Australian triple-negative breast cancer.
23824750 2014
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Germline mutations in the PALB2 gene are population specific and occur with low frequencies in familial breast cancer.
21618343 2011
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
PALB2 and breast cancer: ready for clinical translation!
23935381 2013
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Targeted massively parallel sequencing of a panel of putative breast cancer susceptibility genes in a large cohort of multiple-case breast and ovarian cancer families.
26534844 2016
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair.
24141787 2014
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer.
17200671 2007
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Mutation analysis of PALB2 in BRCA1 and BRCA2-negative breast and/or ovarian cancer families from Eastern Ontario, Canada.
25225577 2014
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination.
20871615 2010
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer.
25452441 2015
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
A PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation.
28240985 2017
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Rare germline mutations in PALB2 and breast cancer risk: a population-based study.
22241545 2012
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
RNA splicing. The human splicing code reveals new insights into the genetic determinants of disease.
25525159 2015
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
PALB2 mutations in German and Russian patients with bilateral breast cancer.
21165770 2011
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
PALB2 sequencing in Italian familial breast cancer cases reveals a high-risk mutation recurrent in the province of Bergamo.
24556926 2014
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Contribution of inherited mutations in the BRCA2-interacting protein PALB2 to familial breast cancer.
21285249 2011
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Comprehensive sequencing of PALB2 in patients with breast cancer suggests PALB2 mutations explain a subset of hereditary breast cancer.
24415441 2014
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer.
26315354 2015
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Breast-cancer risk in families with mutations in PALB2.
25099575 2014
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Exploring the roles of PALB2 at the crossroads of DNA repair and cancer.
24870022 2014
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
26681312 2016