×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
Charcot-Marie-Tooth Disease, Type Ib
1.000
Biomarker
CTD_human
×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
Charcot-Marie-Tooth Disease, Type Ib
1.000
Biomarker
GENOMICS_ENGLAND
×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
Charcot-Marie-Tooth Disease, Type Ib
1.000
Biomarker
GENOMICS_ENGLAND
×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
Charcot-Marie-Tooth Disease, Type Ib
1.000
Biomarker
GENOMICS_ENGLAND
×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
Charcot-Marie-Tooth Disease, Type Ib
1.000
GeneticVariation
CLINVAR
×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
Charcot-Marie-Tooth Disease, Type Ib
1.000
Biomarker
MGD
Mouse P0 gene disruption leads to hypomyelination, abnormal expression of recognition molecules, and degeneration of myelin and axons.
1384988
1992
×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
Charcot-Marie-Tooth Disease, Type Ib
1.000
GeneticVariation
UNIPROT
Deletion of the serine 34 codon from the major peripheral myelin protein P0 gene in Charcot-Marie-Tooth disease type 1B .
7693130
1993
×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
Charcot-Marie-Tooth Disease, Type Ib
1.000
CausalMutation
CLINVAR
Charcot-Marie-Tooth neuropathy type 1B is associated with mutations of the myelin P0 gene.
7693129
1993
×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
Charcot-Marie-Tooth Disease, Type Ib
1.000
GeneticVariation
UNIPROT
Charcot-Marie-Tooth neuropathy type 1B is associated with mutations of the myelin P0 gene.
7693129
1993
×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
Charcot-Marie-Tooth Disease, Type Ib
1.000
GeneticVariation
BEFREE
The same MPZ locus cosegregates with the CMT1B disease gene in a second CMT1B family [total multipoint logarithm of odds (lod) = 11.4 at theta = 0.00] with a splice junction mutation.
7504284
1993
×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
Charcot-Marie-Tooth Disease, Type Ib
1.000
GeneticVariation
UNIPROT
The same MPZ locus cosegregates with the CMT1B disease gene in a second CMT1B family [total multipoint logarithm of odds (lod) = 11.4 at theta = 0.00] with a splice junction mutation.
7504284
1993
×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
Charcot-Marie-Tooth Disease, Type Ib
1.000
GeneticVariation
UNIPROT
Mutation of the myelin P0 gene in Charcot-Marie-tooth neuropathy type 1.
7688964
1993
×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
Charcot-Marie-Tooth Disease, Type Ib
1.000
CausalMutation
CLINVAR
Mutation of the myelin P0 gene in Charcot-Marie-Tooth neuropathy type 1B.
7694726
1993
×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
Charcot-Marie-Tooth Disease, Type Ib
1.000
GeneticVariation
UNIPROT
New mutation of the myelin P0 gene in a pedigree of Charcot-Marie-Tooth neuropathy 1.
7505151
1993
×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
Charcot-Marie-Tooth Disease, Type Ib
1.000
GeneticVariation
BEFREE
The localization of the MPZ gene coincides with the locus for Charcot-Marie-Tooth disease type 1B , determined by linkage analysis.
7503936
1993
×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
Charcot-Marie-Tooth Disease, Type Ib
1.000
Biomarker
BEFREE
Deletion of the serine 34 codon from the major peripheral myelin protein P0 gene in Charcot-Marie-Tooth disease type 1B .
7693130
1993
×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
Charcot-Marie-Tooth Disease, Type Ib
1.000
CausalMutation
CLINVAR
Mutation of the myelin P0 gene in Charcot-Marie-tooth neuropathy type 1.
7688964
1993
×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
Charcot-Marie-Tooth Disease, Type Ib
1.000
GeneticVariation
UNIPROT
Mutation of the myelin P0 gene in Charcot-Marie-Tooth neuropathy type 1B.
7694726
1993
×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
Charcot-Marie-Tooth Disease, Type Ib
1.000
GeneticVariation
BEFREE
While mutation in the gene encoding the major myelin protein, P0 has been associated with CMT1B , CMT1A and HNPP have been shown to be associated with reciprocal recombination events leading either to a large submicroscopic duplication in CMT1A, or the corresponding DNA deletion in HNPP.
7515304
1994
×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
Charcot-Marie-Tooth Disease, Type Ib
1.000
GeneticVariation
UNIPROT
Linkage and mutation analysis in an extended family with Charcot-Marie-Tooth disease type 1B.
7530774
1994
×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
Charcot-Marie-Tooth Disease, Type Ib
1.000
GeneticVariation
UNIPROT
Rapid screening of myelin genes in CMT1 patients by SSCP analysis: identification of new mutations and polymorphisms in the P0 gene.
7527371
1994
×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
Charcot-Marie-Tooth Disease, Type Ib
1.000
CausalMutation
CLINVAR
Rapid screening of myelin genes in CMT1 patients by SSCP analysis: identification of new mutations and polymorphisms in the P0 gene.
7527371
1994
×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
Charcot-Marie-Tooth Disease, Type Ib
1.000
GeneticVariation
UNIPROT
Charcot-Marie-Tooth type 1B neuropathy: third mutation of serine 63 codon in the major peripheral myelin glycoprotein PO gene.
8835320
1995
×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
Charcot-Marie-Tooth Disease, Type Ib
1.000
GeneticVariation
UNIPROT
Mutations in the myelin protein zero gene associated with Charcot-Marie-Tooth disease type 1B .
7550231
1995
×
Entrez Id:
4359
Gene Symbol:
MPZ
MPZ
Charcot-Marie-Tooth Disease, Type Ib
1.000
Biomarker
MGD
Protein zero (P0)-deficient mice show myelin degeneration in peripheral nerves characteristic of inherited human neuropathies.
7581451
1995