×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
Major contribution from recurrent alterations and MSH6 mutations in the Danish Lynch syndrome population.
18566915 2009
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer).
15872200 2005
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
A rapid and cell-free assay to test the activity of lynch syndrome-associated MSH2 and MSH6 missense variants.
22102614 2012
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
MLH1 Ile219Val Polymorphism in Argentinean Families with Suspected Lynch Syndrome.
27606285 2016
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
Germ-line variants identified by next generation sequencing in a panel of estrogen and cancer associated genes correlate with poor clinical outcome in Lynch syndrome patients.
26517685 2015
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
GeneticVariation
UNIPROT
Hereditary nonpolyposis colorectal cancer (HNPCC): eight novel germline mutations in hMSH2 or hMLH1 genes.
9298827 1997
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
Mechanisms of pathogenicity in human MSH2 missense mutants.
18951462 2008
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
Systematic analysis of hMSH2 and hMLH1 in young colon cancer patients and controls.
9718327 1998
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
GeneticVariation
UNIPROT
Novel hMLH1 and hMSH2 germline mutations in African Americans with colorectal cancer.
10386556 1999
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
GeneticVariation
UNIPROT
Sixteen rare sequence variants of the hMLH1 and hMSH2 genes found in a cohort of 254 suspected HNPCC (hereditary non-polyposis colorectal cancer) patients: mutations or polymorphisms?
11726306 2001
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
GeneticVariation
UNIPROT
Mutations of hMLH1 and hMSH2 in patients with suspected hereditary nonpolyposis colorectal cancer: correlation with microsatellite instability and abnormalities of mismatch repair protein expression.
11870161 2002
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
Germline MSH2 and MLH1 mutational spectrum including large rearrangements in HNPCC families from Poland (update study).
16451135 2006
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
Lynch Syndrome in high risk Ashkenazi Jews in Israel.
23990280 2014
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
GeneticVariation
UNIPROT
MSH2 missense mutations and HNPCC syndrome: pathogenicity assessment in a human expression system.
18781619 2008
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
A study on MSH2 and MLH1 mutations in hereditary nonpolyposis colorectal cancer families from the Basque Country, describing four new germline mutations.
19760518 2009
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
A genotype-phenotype correlation in HNPCC: strong predominance of msh2 mutations in 41 patients with Muir-Torre syndrome.
15235030 2004
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
GeneticVariation
UNIPROT
Clinical and molecular characteristics of hereditary non-polyposis colorectal cancer families in Southeast Asia.
15996210 2005
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
GeneticVariation
UNIPROT
Genetic characterization of Chinese hereditary non-polyposis colorectal cancer by DHPLC and multiplex PCR.
15613555 2004
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
GeneticVariation
CLINVAR
Integrated analysis of unclassified variants in mismatch repair genes.
21239990 2011
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
GeneticVariation
CLINVAR
Oligonucleotide-directed mutagenesis screen to identify pathogenic Lynch syndrome-associated MSH2 DNA mismatch repair gene variants.
26951660 2016
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
A multifactorial likelihood model for MMR gene variant classification incorporating probabilities based on sequence bioinformatics and tumor characteristics: a report from the Colon Cancer Family Registry.
22949379 2013
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
MSH2 missense mutations and HNPCC syndrome: pathogenicity assessment in a human expression system.
18781619 2008
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
GeneticVariation
UNIPROT
Influence of selection criteria on mutation detection in patients with hereditary nonpolyposis colorectal cancer.
10375096 1999
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
Splice site mutations in mismatch repair genes and risk of cancer in the general population.
23329266 2013
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
GeneticVariation
UNIPROT
Four novel MSH2 / MLH1 gene mutations in portuguese HNPCC families.
10612836 2000