×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
Biomarker
BEFREE
WRN cell survival and the generation of viable mitotic recombinant progeny could be rescued by expressing wild-type WRN protein or by expressing the bacterial resolvase protein RusA.
12242278
2002
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner's syndrome (WS ) is a premature ageing disease caused by a mutation in the WRN gene.
16362795
2005
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome and mutations of the WRN and LMNA genes in France.
16786514
2006
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome (WS ) is a rare human premature aging disease caused by mutations in the gene encoding the RecQ helicase WRN .
17284601
2007
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
Biomarker
BEFREE
Werner syndrome (WS ) is a premature aging and cancer-prone disease caused by loss of the RecQ helicase WRN protein.
17624410
2007
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome is an autosomal recessive disease of premature aging caused by a polymorphic C1367T mutation in the Werner (WRN ) gene.
20808731
2010
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome (WS ) is an autosomal recessive progeroid disorder caused by mutations in the WRN DNA helicase.
22188495
2012
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
Biomarker
BEFREE
Werner syndrome (WS ) is a disorder characterized by features of premature aging and increased cancer that is caused by loss of the RecQ helicase WRN .
22871734
2012
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome is caused by mutations in the DNA repair Werner helicase (WRN ) gene and characterized by accelerated aging including cataracts.
23334603
2013
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome (WS) is a rare autosomal recessive disorder caused by mutations in the WRN gene.
23583337
2013
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome is genetically linked to mutations in WRN that encodes a DNA helicase-nuclease believed to operate at stalled replication forks.
23867477
2013
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome (WS ) is a premature aging disorder caused by WRN protein deficiency.
25931448
2015
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome (i.e., adult progeria) is a rare autosomal recessive disorder caused by mutations of the WRN gene, which is characterized by the premature appearance of features associated with normal aging and cancer predisposition.
27931782
2017
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome (WS ) is a progeroid-like syndrome caused by WRN gene mutations.
28158503
2017
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome (WS ) is a rare inheritable progeroid syndrome caused by a mutation in the WRN gene.
28738022
2017
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome (WRN ) gene variants and their association with altered function and age-associated diseases.
29146545
2018
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
Werner syndrome is a rare autosomal recessive disorder where Werner (WRN ) gene is mutated.
31085421
2019
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
WRN is encoded by the gene that when mutated causes Werner's syndrome .
10540192
1999
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
Biomarker
BEFREE
WRN or telomerase constructs reverse 4-nitroquinoline 1-oxide sensitivity in transformed Werner syndrome fibroblasts.
10811112
2000
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
Biomarker
BEFREE
WRN , the gene defective in WS , encodes a 1432 amino acid protein (hWRN) with intrinsic 3'-->5' DNA helicase activity.
10871373
2000
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
Biomarker
BEFREE
WRN and BLM genes causing WS and BS, encode proteins that are closely related to the RecQ helicase.
11840341
2002
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
Biomarker
BEFREE
WRN -1 is the Caenorhabditis elegans homolog of the human Werner syndrome protein, a RecQ helicase, mutations of which are associated with premature aging and increased genome instability.
20062519
2010
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
WRN mutations in Werner syndrome patients: genomic rearrangements, unusual intronic mutations and ethnic-specific alterations.
20443122
2010
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
GeneticVariation
BEFREE
A 55-year-old patient with WS was studied and it was found that a deletion mutation of exon 26 of the WRN gene was not associated with CNS pathology, such as amyloid plaques or NFT.
12722926
2003
×
Entrez Id:
7486
Gene Symbol:
WRN
WRN
Werner Syndrome
1.000
Biomarker
BEFREE
A Werner syndrome protein homolog in C. elegans (WRN -1) was immunolocalized to the nuclei of germ cells, embryonic cells, and many other cells of larval and adult worms.
15115755
2004