Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.600 GeneticVariation UNIPROT Recurrent HOXB13 mutations in the Dutch population do not associate with increased breast cancer risk. 27424772

2016

Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.600 GeneticVariation UNIPROT For example, a recent study suggested that one cannot adequately impute the HOXB13 G84E mutation associated with prostate cancer risk (carrier frequency of 0.0034 in European ancestry participants in the 1000 Genomes Project). 25629170

2015

Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.600 Biomarker CTD_human The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis. 26457646

2015

Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.600 Biomarker CTD_human Human HOX gene disorders. 24239177

2014

Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.600 Biomarker CTD_human Together, our results suggest that rs339331 affects prostate cancer risk by altering RFX6 expression through a functional interaction with the prostate cancer susceptibility gene HOXB13. 24390282

2014

Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.600 GeneticVariation UNIPROT A recently identified germline mutation G84E in HOXB13 was shown to increase the risk of prostate cancer. 23292082

2013

Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.600 GeneticVariation UNIPROT To examine this finding in a large international sample of prostate cancer families, we genotyped this mutation and 14 other SNPs in or flanking HOXB13 in 2,443 prostate cancer families recruited by the International Consortium for Prostate Cancer Genetics (ICPCG). 23064873

2013

Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.600 GeneticVariation UNIPROT Our study confirmed the association between the G84E mutation of HOXB13 and risk of prostate cancer among subjects of European descent. 22714738

2012

Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.600 Biomarker CTD_human We also report results for a previously described HOXB13 variant (rs138213197[T]), confirming it as a prostate cancer risk variant in populations from across Europe. 23104005

2012

Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.600 GeneticVariation UNIPROT Germline mutations in HOXB13 and prostate-cancer risk. 22236224

2012