Source: GWASCAT

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3075
Gene Symbol: CFH
CFH
CUI: C0242383
Disease: Age related macular degeneration
Age related macular degeneration 		0.500 GeneticVariation GWASCAT The CFH gene is located on chromosome 1 in a region repeatedly linked to AMD in family-based studies. 15761122

2005
Entrez Id: 9722
Gene Symbol: NOS1AP
NOS1AP
CUI: C0429028
Disease: QT interval feature (observable entity)
QT interval feature (observable entity) 		0.100 GeneticVariation GWASCAT A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization. 16648850

2006
Entrez Id: 5654
Gene Symbol: HTRA1
HTRA1
CUI: C0242383
Disease: Age related macular degeneration
Age related macular degeneration 		0.500 GeneticVariation GWASCAT Here we report that a single-nucleotide polymorphism in the promoter region of HTRA1, a serine protease gene on chromosome 10q26, is a major genetic risk factor for wet AMD. 17053108

2006
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
CUI: C0021390
Disease: Inflammatory Bowel Diseases
Inflammatory Bowel Diseases 		0.500 GeneticVariation GWASCAT A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. 17068223

2006
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 GeneticVariation GWASCAT A genome-wide association study identifies novel risk loci for type 2 diabetes. 17293876

2007
Entrez Id: 169026
Gene Symbol: SLC30A8
SLC30A8
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.500 GeneticVariation GWASCAT A genome-wide association study identifies novel risk loci for type 2 diabetes. 17293876

2007
Entrez Id: 100750225
Gene Symbol: PCAT1
PCAT1
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.200 GeneticVariation GWASCAT Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. 17401363

2007
Entrez Id: 5462
Gene Symbol: POU5F1B
POU5F1B
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.150 GeneticVariation GWASCAT Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. 17401363

2007
Entrez Id: 101805488
Gene Symbol: CCAT2
CCAT2
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.110 GeneticVariation GWASCAT Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. 17401363

2007
Entrez Id: 727677
Gene Symbol: CASC8
CASC8
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.100 GeneticVariation GWASCAT Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. 17401363

2007
Entrez Id: 100750225
Gene Symbol: PCAT1
PCAT1
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.200 GeneticVariation GWASCAT Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. 17401366

2007
Entrez Id: 101867536
Gene Symbol: PRNCR1
PRNCR1
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.170 GeneticVariation GWASCAT Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. 17401366

2007
Entrez Id: 727677
Gene Symbol: CASC8
CASC8
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.100 GeneticVariation GWASCAT Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. 17401366

2007
Entrez Id: 103021165
Gene Symbol: CASC19
CASC19
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.100 GeneticVariation GWASCAT Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. 17401366

2007
Entrez Id: 3613
Gene Symbol: IMPA2
IMPA2
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.100 GeneticVariation GWASCAT A genome-wide genotyping study in patients with ischaemic stroke: initial analysis and data release. 17434096

2007
Entrez Id: 79068
Gene Symbol: FTO
FTO
CUI: C1305855
Disease: Body mass index
Body mass index 		0.100 GeneticVariation GWASCAT A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. 17434869

2007
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		1.000 GeneticVariation GWASCAT Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. 17435756

2007
Entrez Id: 149233
Gene Symbol: IL23R
IL23R
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.700 GeneticVariation GWASCAT Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. 17435756

2007
Entrez Id: 55054
Gene Symbol: ATG16L1
ATG16L1
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.700 GeneticVariation GWASCAT Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. 17435756

2007
Entrez Id: 400757
Gene Symbol: C1orf141
C1orf141
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.100 GeneticVariation GWASCAT Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. 17435756

2007
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		1.000 GeneticVariation GWASCAT Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4. 17447842

2007
Entrez Id: 149233
Gene Symbol: IL23R
IL23R
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.700 GeneticVariation GWASCAT Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4. 17447842

2007
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 GeneticVariation GWASCAT We conducted a genome-wide association study for type 2 diabetes (T2D) in Icelandic cases and controls, and we found that a previously described variant in the transcription factor 7-like 2 gene (TCF7L2) gene conferred the most significant risk. 17460697

2007
Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 GeneticVariation GWASCAT In addition to confirming two recently identified risk variants, we identified a variant in the CDKAL1 gene that was associated with T2D in individuals of European ancestry (allele-specific odds ratio (OR) = 1.20 (95% confidence interval, 1.13-1.27), P = 7.7 x 10(-9)) and individuals from Hong Kong of Han Chinese ancestry (OR = 1.25 (1.11-1.40), P = 0.00018). 17460697

2007
Entrez Id: 3767
Gene Symbol: KCNJ11
KCNJ11
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.900 GeneticVariation GWASCAT Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. 17463246

2007